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Literature DB >> 27048564

IP3 receptors: Take four IP3 to open.

Abstract

Inositol 1,4,5-trisphosphate receptors (IP3Rs) and ryanodine receptors are the channels responsible for Ca(2+)release from the endoplasmic and sarcoplasmic reticulum. Research inScience Signalingby Alzayadyet al show that all four IP3-binding sites within the tetrameric IP3R must bind IP3before the channel can open, which has important consequences for the distribution of both IP3and IP3R activity within cells.

Entities: Chemical Gene Species

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Year: 2016 PMID： 27048564 PMCID： PMC5019202 DOI： 10.1126/scisignal.aaf6029

Source DB: PubMed Journal: Sci Signal ISSN： 1945-0877 Impact factor: 8.192

22 in total

Review 1. IP(3) receptors: toward understanding their activation.

Authors: Colin W Taylor; Stephen C Tovey
Journal: Cold Spring Harb Perspect Biol Date: 2010-10-27 Impact factor: 10.005

2. Molecular characterization of the inositol 1,4,5-trisphosphate receptor pore-forming segment.

Authors: Zachary T Schug; Paula C A da Fonseca; Cunnigaiper D Bhanumathy; Larry Wagner; Xianchao Zhang; Bradley Bailey; Edward P Morris; David I Yule; Suresh K Joseph
Journal: J Biol Chem Date: 2007-11-19 Impact factor: 5.157

3. Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

Authors: Kamil J Alzayady; Larry E Wagner; Rahul Chandrasekhar; Alina Monteagudo; Ronald Godiska; Gregory G Tall; Suresh K Joseph; David I Yule
Journal: J Biol Chem Date: 2013-08-16 Impact factor: 5.157

Review 4. Ryanodine receptors: structure and function.

Authors: Filip Van Petegem
Journal: J Biol Chem Date: 2012-07-20 Impact factor: 5.157

5. Binding of inositol 1,4,5-trisphosphate (IP3) and adenophostin A to the N-terminal region of the IP3 receptor: thermodynamic analysis using fluorescence polarization with a novel IP3 receptor ligand.

Authors: Zhao Ding; Ana M Rossi; Andrew M Riley; Taufiq Rahman; Barry V L Potter; Colin W Taylor
Journal: Mol Pharmacol Date: 2010-03-09 Impact factor: 4.436

6. Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand.

Authors: Ivan Bosanac; Jean-René Alattia; Tapas K Mal; Jenny Chan; Susanna Talarico; Frances K Tong; Kit I Tong; Fumio Yoshikawa; Teiichi Furuichi; Miwako Iwai; Takayuki Michikawa; Katsuhiko Mikoshiba; Mitsuhiko Ikura
Journal: Nature Date: 2002-11-17 Impact factor: 49.962

7. Highly cooperative opening of calcium channels by inositol 1,4,5-trisphosphate.

Authors: T Meyer; D Holowka; L Stryer
Journal: Science Date: 1988-04-29 Impact factor: 47.728

Review 8. Overview and future of single particle electron cryomicroscopy.

Authors: Richard Henderson
Journal: Arch Biochem Biophys Date: 2015-03-18 Impact factor: 4.013

9. Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.

Authors: Zhen Yan; Xiaochen Bai; Chuangye Yan; Jianping Wu; Zhangqiang Li; Tian Xie; Wei Peng; Changcheng Yin; Xueming Li; Sjors H W Scheres; Yigong Shi; Nieng Yan
Journal: Nature Date: 2014-12-15 Impact factor: 49.962

10. Selective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMP.

Authors: Stephen C Tovey; Skarlatos G Dedos; Emily J A Taylor; Jarrod E Church; Colin W Taylor
Journal: J Cell Biol Date: 2008-10-20 Impact factor: 10.539

15 in total

Review 1. Structure and Function of IP₃ Receptors.

Authors: David L Prole; Colin W Taylor
Journal: Cold Spring Harb Perspect Biol Date: 2019-04-01 Impact factor: 10.005

2. All three IP₃ receptor isoforms generate Ca²⁺ puffs that display similar characteristics.

Authors: Jeffrey T Lock; Kamil J Alzayady; David I Yule; Ian Parker
Journal: Sci Signal Date: 2018-12-18 Impact factor: 8.192

3. Sexual Dimorphism in a Reciprocal Interaction of Ryanodine and IP₃ Receptors in the Induction of Hyperalgesic Priming.

Authors: Eugen V Khomula; Luiz F Ferrari; Dionéia Araldi; Jon D Levine
Journal: J Neurosci Date: 2017-01-23 Impact factor: 6.167

10. Synaptic neuron-astrocyte communication is supported by an order of magnitude analysis of inositol tris-phosphate diffusion at the nanoscale in a model of peri-synaptic astrocyte projection.

Authors: Pavel Montes de Oca Balderas; Horacio Montes de Oca Balderas
Journal: BMC Biophys Date: 2018-02-12 Impact factor: 4.778

IP3 receptors: Take four IP3 to open.

Review 1. IP(3) receptors: toward understanding their activation.

2. Molecular characterization of the inositol 1,4,5-trisphosphate receptor pore-forming segment.

3. Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

Review 4. Ryanodine receptors: structure and function.

5. Binding of inositol 1,4,5-trisphosphate (IP3) and adenophostin A to the N-terminal region of the IP3 receptor: thermodynamic analysis using fluorescence polarization with a novel IP3 receptor ligand.

6. Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand.

7. Highly cooperative opening of calcium channels by inositol 1,4,5-trisphosphate.

Review 8. Overview and future of single particle electron cryomicroscopy.

9. Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.

10. Selective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMP.

Review 1. Structure and Function of IP₃ Receptors.

2. All three IP₃ receptor isoforms generate Ca²⁺ puffs that display similar characteristics.

3. Sexual Dimorphism in a Reciprocal Interaction of Ryanodine and IP₃ Receptors in the Induction of Hyperalgesic Priming.

4. Hindered cytoplasmic diffusion of inositol trisphosphate restricts its cellular range of action.

Review 5. Spatial-temporal patterning of Ca²⁺ signals by the subcellular distribution of IP₃ and IP₃ receptors.

6. Dynamic Ca²⁺ imaging with a simplified lattice light-sheet microscope: A sideways view of subcellular Ca²⁺ puffs.

7. TNFα induces Ca²⁺ influx to accelerate extrinsic apoptosis in hepatocellular carcinoma cells.

Review 8. Bcl-2-Protein Family as Modulators of IP₃ Receptors and Other Organellar Ca²⁺ Channels.

9. Endogenous signalling pathways and caged IP₃ evoke Ca²⁺ puffs at the same abundant immobile intracellular sites.

10. Synaptic neuron-astrocyte communication is supported by an order of magnitude analysis of inositol tris-phosphate diffusion at the nanoscale in a model of peri-synaptic astrocyte projection.

Review 1. IP(3) receptors: toward understanding their activation.

Review 4. Ryanodine receptors: structure and function.

Review 8. Overview and future of single particle electron cryomicroscopy.

Review 1. Structure and Function of IP3 Receptors.

Review 5. Spatial-temporal patterning of Ca2+ signals by the subcellular distribution of IP3 and IP3 receptors.

Review 8. Bcl-2-Protein Family as Modulators of IP3 Receptors and Other Organellar Ca2+ Channels.

Review 1. Structure and Function of IP₃ Receptors.

Review 5. Spatial-temporal patterning of Ca²⁺ signals by the subcellular distribution of IP₃ and IP₃ receptors.

Review 8. Bcl-2-Protein Family as Modulators of IP₃ Receptors and Other Organellar Ca²⁺ Channels.