Literature DB >> 27047218

The effect of platelet-rich plasma injection on lateral epicondylitis following failed conservative management.

Milos Brkljac1, Shyam Kumar2, Dale Kalloo2, Kiran Hirehal2.   

Abstract

OBJECTIVE: We assessed the effect PRP injection on pain and function in patients with lateral epicondylitis where conservative management had failed.
METHODS: We prospectively reviewed 34 patients. The mean follow-up was 26 weeks (range 6-114 weeks). We used the Oxford Elbow Score (OES) and progression to surgery to assess outcomes.
RESULTS: 88.2% improved their OES. 8.8% reported symptom progression. One patient had no change. No patients suffered adverse reactions. Two patients underwent an open release procedure. One had the injection repeated.
CONCLUSION: An injection of PRP improves pain and function in patients suffering from LE where conservative management has failed.

Entities:  

Keywords:  ASES, American Shoulder and Elbow Surgeons; AWB, autologous whole blood; DASH, disabilities of arm, shoulder and hand; ECRB, Extensor Carpe Radialis Brevis; LE, lateral epicondylitis; Lateral epicondylitis; Lateral tendinosis; MCID, minimal clinically important difference; NSAIDs, non-steroidal anti-inflammatorys; OES, Oxford Elbow Score; PRP, platelet-rich plasma; Platelet-rich plasma; Tennis elbow; VAS, visual-analogue score

Year:  2015        PMID: 27047218      PMCID: PMC4796570          DOI: 10.1016/j.jor.2015.10.018

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  19 in total

Review 1.  Tendinosis of the elbow (tennis elbow). Clinical features and findings of histological, immunohistochemical, and electron microscopy studies.

Authors:  B S Kraushaar; R P Nirschl
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2.  Time to abandon the "tendinitis" myth.

Authors:  K M Khan; J L Cook; P Kannus; N Maffulli; S F Bonar
Journal:  BMJ       Date:  2002-03-16

3.  Mobilisation with movement and exercise, corticosteroid injection, or wait and see for tennis elbow: randomised trial.

Authors:  Leanne Bisset; Elaine Beller; Gwendolen Jull; Peter Brooks; Ross Darnell; Bill Vicenzino
Journal:  BMJ       Date:  2006-09-29

4.  Comparison of autologous blood, corticosteroid, and saline injection in the treatment of lateral epicondylitis: a prospective, randomized, controlled multicenter study.

Authors:  Jennifer Moriatis Wolf; Kagan Ozer; Frank Scott; Michael J V Gordon; Allison E Williams
Journal:  J Hand Surg Am       Date:  2011-06-25       Impact factor: 2.230

5.  Ongoing positive effect of platelet-rich plasma versus corticosteroid injection in lateral epicondylitis: a double-blind randomized controlled trial with 2-year follow-up.

Authors:  Taco Gosens; Joost C Peerbooms; Wilbert van Laar; Brenda L den Oudsten
Journal:  Am J Sports Med       Date:  2011-03-21       Impact factor: 6.202

6.  Efficacy of platelet-rich plasma for chronic tennis elbow: a double-blind, prospective, multicenter, randomized controlled trial of 230 patients.

Authors:  Allan K Mishra; Nebojsa V Skrepnik; Scott G Edwards; Grant L Jones; Steven Sampson; Doug A Vermillion; Matthew L Ramsey; David C Karli; Arthur C Rettig
Journal:  Am J Sports Med       Date:  2013-07-03       Impact factor: 6.202

7.  Growth factor-based therapies provide additional benefit beyond physical therapy in resistant elbow tendinopathy: a prospective, single-blind, randomised trial of autologous blood injections versus platelet-rich plasma injections.

Authors:  Leon Creaney; Andrew Wallace; Mark Curtis; David Connell
Journal:  Br J Sports Med       Date:  2011-03-15       Impact factor: 13.800

Review 8.  The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: a review of the literature.

Authors:  J Alsousou; M Thompson; P Hulley; A Noble; K Willett
Journal:  J Bone Joint Surg Br       Date:  2009-08

Review 9.  A systematic review of four injection therapies for lateral epicondylosis: prolotherapy, polidocanol, whole blood and platelet-rich plasma.

Authors:  D Rabago; T M Best; A E Zgierska; E Zeisig; M Ryan; D Crane
Journal:  Br J Sports Med       Date:  2008-11-21       Impact factor: 13.800

10.  Effect of Platelet-Rich Plasma (PRP) versus Autologous Whole Blood on Pain and Function Improvement in Tennis Elbow: A Randomized Clinical Trial.

Authors:  Seyed Ahmad Raeissadat; Leyla Sedighipour; Seyed Mansoor Rayegani; Mohammad Hasan Bahrami; Masume Bayat; Rosa Rahimi
Journal:  Pain Res Treat       Date:  2014-01-20
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  5 in total

Review 1.  Platelet-rich plasma in tendon-related disorders: results and indications.

Authors:  Giuseppe Filardo; Berardo Di Matteo; Elizaveta Kon; Giulia Merli; Maurilio Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-09-24       Impact factor: 4.342

2.  Platelet-Rich Plasma Injection With Percutaneous Needling for Recalcitrant Lateral Epicondylitis: Comparison of Tenotomy and Fenestration Techniques.

Authors:  Michael P Gaspar; Michael A Motto; Sarah Lewis; Sidney M Jacoby; Randall W Culp; A Lee Osterman; Patrick M Kane
Journal:  Orthop J Sports Med       Date:  2017-12-06

Review 3.  Platelet-Rich Plasma Injections as an Alternative to Surgery in Treating Patients With Medial Epicondylitis: A Systematic Review.

Authors:  Wael M Alzahrani
Journal:  Cureus       Date:  2022-08-25

4.  A comparative study to evaluate the efficacy of platelet-rich plasma and triamcinolone to treat tennis elbow.

Authors:  Vanamali B Seetharamaiah; Amrit Gantaguru; Sunil Basavarajanna
Journal:  Indian J Orthop       Date:  2017 May-Jun       Impact factor: 1.251

5.  Platelet-Rich Plasma Is an Equal Alternative to Surgery in the Treatment of Type 1 Medial Epicondylitis.

Authors:  Hunter L Bohlen; Zachary E Schwartz; Victor J Wu; Stephen G Thon; Zachary J Finley; Michael J O'Brien; Felix H Savoie
Journal:  Orthop J Sports Med       Date:  2020-03-25
  5 in total

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