Literature DB >> 27046816

GPCR Signaling: β-arrestins Kiss and Remember.

Ravi Ranjan1, Pragya Gupta1, Arun K Shukla2.   

Abstract

β-arrestin-dependent activation of the ERK MAP kinase downstream of GPCRs typically originates from internalized receptor-β-arrestin-ERK complexes. A new study now reports that β-arrestin 2 is sufficiently 'primed' after 'kissing' the β1-adrenergic receptor to initiate ERK activation even in the absence of formation of the receptor-β-arrestin-ERK complex and receptor internalization.
Copyright © 2016 Elsevier Ltd. All rights reserved.

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Year:  2016        PMID： 27046816     DOI： 10.1016/j.cub.2016.02.056

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  11 in total

1.  Muscarinic receptor regulates extracellular signal regulated kinase by two modes of arrestin binding.

Authors:  Seung-Ryoung Jung; Christopher Kushmerick; Jong Bae Seo; Duk-Su Koh; Bertil Hille
Journal:  Proc Natl Acad Sci U S A       Date:  2017-06-26       Impact factor: 11.205

2.  Measuring agonist-induced ERK MAP kinase phosphorylation for G-protein-coupled receptors.

Authors:  Punita Kumari; Hemlata Dwivedi; Mithu Baidya; Arun K Shukla
Journal:  Methods Cell Biol       Date:  2018-11-19       Impact factor: 1.441

3.  Scavenger Receptor C Mediates Phagocytosis of White Spot Syndrome Virus and Restricts Virus Proliferation in Shrimp.

Authors:  Ming-Chong Yang; Xiu-Zhen Shi; Hui-Ting Yang; Jie-Jie Sun; Ling Xu; Xian-Wei Wang; Xiao-Fan Zhao; Jin-Xing Wang
Journal:  PLoS Pathog       Date:  2016-12-27       Impact factor: 6.823

Review 4.  The role and mechanism of β‑arrestins in cancer invasion and metastasis (Review).

Authors:  Qing Song; Qing Ji; Qi Li
Journal:  Int J Mol Med       Date:  2017-11-27       Impact factor: 4.101

5.  Systemic Sympathoexcitation Was Associated with Paraventricular Hypothalamic Phosphorylation of Synaptic CaMKIIα and MAPK/ErK.

Authors:  Olalekan M Ogundele; Fernando A Rosa; Rohan Dharmakumar; Charles C Lee; Joseph Francis
Journal:  Front Neurosci       Date:  2017-08-03       Impact factor: 4.677

Review 6.  G Protein-Coupled Receptor Kinase 2 (GRK2) as a Potential Therapeutic Target in Cardiovascular and Metabolic Diseases.

Authors:  Cristina Murga; Alba C Arcones; Marta Cruces-Sande; Ana M Briones; Mercedes Salaices; Federico Mayor
Journal:  Front Pharmacol       Date:  2019-02-19       Impact factor: 5.810

Review 7.  Nitric Oxide and S-Nitrosylation in Cardiac Regulation: G Protein-Coupled Receptor Kinase-2 and β-Arrestins as Targets.

Authors:  Gizem Kayki-Mutlu; Walter J Koch
Journal:  Int J Mol Sci       Date:  2021-01-07       Impact factor: 5.923

Review 8.  QR code model: a new possibility for GPCR phosphorylation recognition.

Authors:  Hao Chen; Suli Zhang; Xi Zhang; Huirong Liu
Journal:  Cell Commun Signal       Date:  2022-03-02       Impact factor: 5.712

9.  Functional competence of a partially engaged GPCR-β-arrestin complex.

Authors:  Punita Kumari; Ashish Srivastava; Ramanuj Banerjee; Eshan Ghosh; Pragya Gupta; Ravi Ranjan; Xin Chen; Bhagyashri Gupta; Charu Gupta; Deepika Jaiman; Arun K Shukla
Journal:  Nat Commun       Date:  2016-11-09       Impact factor: 14.919

10.  A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis.

Authors:  Eshan Ghosh; Ashish Srivastava; Mithu Baidya; Punita Kumari; Hemlata Dwivedi; Kumari Nidhi; Ravi Ranjan; Shalini Dogra; Akiko Koide; Prem N Yadav; Sachdev S Sidhu; Shohei Koide; Arun K Shukla
Journal:  Nat Nanotechnol       Date:  2017-10-02       Impact factor: 39.213
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