Literature DB >> 27046001

Choroidal metastasis as a presenting manifestation of a lung adenocarcinoma with response to afatinib.

M Contreras-Díaz1, A Medina-Tapia2, G Martínez-Bernal3, T Rueda-Rueda2, F López-Herrero2, F E Molina-Socola2, J L Sánchez-Vicente2.   

Abstract

CASE REPORT: We present the case of a 55-year-old man with a non-small cell lung adenocarcinoma, who presented with choroidal metastasis. The patient showed a decrease in visual acuity. His evaluation revealed unilateral choroidal metastasis secondary to carcinoma of the lung. The patient received afatinib with complete regression of choroidal metastasis after one year follow-up. DISCUSSION: Choroidal metastasis may be the initial sign of lung cancer. This case highlights the importance of a thorough systemic evaluation in patients with choroidal tumours. Afatinib was effective against choroidal metastasis of a lung adenocarcinoma with EFGR mutation.
Copyright © 2016 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.

Entities:  

Keywords:  Adenocarcinoma de pulmón; Afatinib; Choroidal metastasis; Choroidal tumours; EFGR mutation; Lung adenocarcinoma; Metástasis coroidea; Mutación EFGR; Tumores coroideos

Mesh:

Substances:

Year:  2016        PMID: 27046001     DOI: 10.1016/j.oftal.2016.03.002

Source DB:  PubMed          Journal:  Arch Soc Esp Oftalmol        ISSN: 0365-6691


  1 in total

1.  Epidermal growth factor receptor-mutant non-small cell lung Cancer and Choroidal metastases: long-term outcome and response to epidermal growth factor receptor tyrosine kinase inhibitors.

Authors:  Clémentine Bouchez; Johan Pluvy; Ghassen Soussi; Marina Nguenang; Solenn Brosseau; Morgan Tourne; Mégane Collin; Nathalie Théou-Anton; Alice Guyard; Jamila Ammar; Antoine Khalil; Gérard Zalcman; Valérie Gounant
Journal:  BMC Cancer       Date:  2020-12-03       Impact factor: 4.430

  1 in total

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