| Literature DB >> 27044327 |
Elisa Sheng1, Daniela Witten2, Xiao-Hua Zhou3.
Abstract
In a multivariate setting, we consider the task of identifying features whose correlations with the other features differ across conditions. Such correlation shifts may occur independently of mean shifts, or differences in the means of the individual features across conditions. Previous approaches for detecting correlation shifts consider features simultaneously, by computing a correlation-based test statistic for each feature. However, since correlations involve two features, such approaches do not lend themselves to identifying which feature is the culprit. In this article, we instead consider a serial testing approach, by comparing columns of the sample correlation matrix across two conditions, and removing one feature at a time. Our method provides a novel perspective and favorable empirical results compared with competing approaches.Keywords: Correlation matrix; Differential correlation; Feature selection; Hypothesis testing; Wald test
Mesh:
Year: 2016 PMID: 27044327 PMCID: PMC5031944 DOI: 10.1093/biostatistics/kxw013
Source DB: PubMed Journal: Biostatistics ISSN: 1465-4644 Impact factor: 5.899