Literature DB >> 27044042

Isolation and Propagation of Glioma Stem Cells from Acutely Resected Tumors.

Jinkyu Jung1, Mark R Gilbert2, Deric M Park3.   

Abstract

Gliomas are characterized by striking intratumoral cellular heterogeneity. A consistent method to isolate undifferentiated GSC fraction from clinical specimens provides an opportunity to establish in vitro models that more closely mirror the in vivo state compared to traditional serum containing culture methods. Here we describe techniques involved with isolation, identification, and expansion of human malignant glioma-derived stem cells using a serum-free growth condition.

Entities:  

Keywords:  GBM; Glioblastoma multiforme; Glioma stem cell; N2 medium; Neural stem cell; Serum-free cell culture

Mesh：

Year:  2016        PMID： 27044042     DOI： 10.1007/7651_2016_342

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  4 in total

Review 1.  Off the Clock: the Non-canonical Roles of Cyclin-Dependent Kinases in Neural and Glioma Stem Cell Self-Renewal.

Authors:  Ling-Kai Shih; Subhas Mukherjee; Daniel J Brat
Journal:  Mol Neurobiol       Date:  2022-08-31       Impact factor: 5.682

2.  Cardiac glycosides suppress the maintenance of stemness and malignancy via inhibiting HIF-1α in human glioma stem cells.

Authors:  Dae-Hee Lee; Sang Cheul Oh; Amber J Giles; Jinkyu Jung; Mark R Gilbert; Deric M Park
Journal:  Oncotarget       Date:  2017-06-20

Review 3.  Therapeutic Potential for Bone Morphogenetic Protein 4 in Human Malignant Glioma.

Authors:  Guifa Xi; Benjamin Best; Barbara Mania-Farnell; Charles David James; Tadanori Tomita
Journal:  Neoplasia       Date:  2017-03-07       Impact factor: 5.715

4.  The construction of the multifunctional targeting ursolic acids liposomes and its apoptosis effects to C6 glioma stem cells.

Authors:  Xue Ying; Yahua Wang; Haolun Xu; Xia Li; Helu Yan; Hui Tang; Chen Wen; Yingchun Li
Journal:  Oncotarget       Date:  2017-08-02
  4 in total

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