Literature DB >> 27043834

Wilms Tumor: An Uncommon Entity in the Adult Patient.

Fade Mahmoud1, M Brandon Allen2, Roni Cox3, Rodney Davis4.   

Abstract

Wilms tumor, the most common kidney tumor in children, is rarely seen in adults, making it a challenge for the adult oncologist to diagnose and treat. Unlike with renal cell carcinoma, patients with Wilms tumor should receive adjuvant chemotherapy with or without radiation therapy. Adult oncologists may not be familiar with pediatric oncology protocols, so it is important to consult with pediatric oncologists who have more experience in this disease. Multimodal therapy based on pediatric protocols improved the outcomes of adults with Wilms tumor worldwide. We report a rare case of a 24-year-old woman with a slow-growing mass of the left kidney during a 4-year period. The mass was surgically removed and final diagnosis confirmed by pathology to be Wilms tumor. The patient received adjuvant chemotherapy and has been free of disease since 2014.

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Year:  2016        PMID: 27043834      PMCID: PMC4867842          DOI: 10.7812/TPP/15-110

Source DB:  PubMed          Journal:  Perm J        ISSN: 1552-5767


  9 in total

Review 1.  Metanephric adenofibroma: report of a case and review of the literature.

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Journal:  Am J Surg Pathol       Date:  1999-06       Impact factor: 6.394

2.  Metanephric adenoma, nephrogenic rests, and Wilms' tumor: a histologic and immunophenotypic comparison.

Authors:  T E Muir; J C Cheville; D J Lager
Journal:  Am J Surg Pathol       Date:  2001-10       Impact factor: 6.394

3.  Adult Wilms' tumor: case report, management, prognosis.

Authors:  K Weichert-Jacobsen; I Papadopoulos; C Skrezek; H Wand
Journal:  Urol Int       Date:  1995       Impact factor: 2.089

Review 4.  Genetic events in the development of Wilms' tumor.

Authors:  M J Coppes; D A Haber; P E Grundy
Journal:  N Engl J Med       Date:  1994-09-01       Impact factor: 91.245

Review 5.  Current therapy for Wilms' tumor.

Authors:  Monika L Metzger; Jeffrey S Dome
Journal:  Oncologist       Date:  2005 Nov-Dec

Review 6.  Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene.

Authors:  Vicki Huff
Journal:  Nat Rev Cancer       Date:  2011-01-20       Impact factor: 60.716

Review 7.  Children's Oncology Group's 2013 blueprint for research: renal tumors.

Authors:  Jeffrey S Dome; Conrad V Fernandez; Elizabeth A Mullen; John A Kalapurakal; James I Geller; Vicki Huff; Eric J Gratias; David B Dix; Peter F Ehrlich; Geetika Khanna; Marcio H Malogolowkin; James R Anderson; Arlene Naranjo; Elizabeth J Perlman
Journal:  Pediatr Blood Cancer       Date:  2012-12-19       Impact factor: 3.167

8.  Adult Wilms tumor: effect of combined therapy on survival.

Authors:  R L Byrd; A E Evans; G J D'Angio
Journal:  J Urol       Date:  1982-04       Impact factor: 7.450

9.  Wilms' tumor in adults: results of the Society of Pediatric Oncology (SIOP) 93-01/Society for Pediatric Oncology and Hematology (GPOH) Study.

Authors:  Harald Reinhard; Schahin Aliani; Christian Ruebe; Michael Stöckle; Ivo Leuschner; Norbert Graf
Journal:  J Clin Oncol       Date:  2004-11-15       Impact factor: 44.544

  9 in total
  1 in total

1.  Evaluating Established Roles, Future Perspectives and Methodological Heterogeneity for Wilms' Tumor 1 (WT1) Antigen Detection in Adult Renal Cell Carcinoma, Using a Novel N-Terminus Targeted Antibody (Clone WT49).

Authors:  Dorin Novacescu; Talida Georgiana Cut; Alin Adrian Cumpanas; Silviu Constantin Latcu; Razvan Bardan; Ovidiu Ferician; Cosmin-Ciprian Secasan; Andrei Rusmir; Marius Raica
Journal:  Biomedicines       Date:  2022-04-15
  1 in total

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