| Literature DB >> 27043213 |
Xiaoyu Li1, Xiaoyu Liu1, Xiaozhen Jiao1, Hongguang Yang1, Yangyang Yao1, Ping Xie1.
Abstract
(±)-Lingzhiol has been synthesized from commercially available 5,8-dimethoxytetralone in seven steps with an overall yield of 10.3% via an unprecedented acid-catalyzed semipinacol-type rearrangement. In addition, a novel strategy for the construction of the tetracyclic 5/5/6/6 core structure of lingzhiol has been developed via a tandem rearrangement/reduction/lactonization reaction.Entities:
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Year: 2016 PMID： 27043213 DOI： 10.1021/acs.orglett.6b00542
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005