Literature DB >> 27042594

Spindle Cell Carcinoma of the Mandibular Gingiva - A Case Report.

Sangeeta R Patankar1, Pratyusha P Gaonkar2, Prachi R Bhandare2, Nidhi Tripathi2, Gokul Sridharan3.   

Abstract

Spindle cell carcinoma is a malignancy of epithelial origin often mimicking its mesenchymal counterpart thus posing a diagnostic challenge. It is a rare biphasic malignant tumour mostly encountered in the upper aerodigestive tract. The chief differential diagnoses of spindle cell carcinoma are true superficial sarcomas and they especially need to be differentiated from fibrosarcoma. This presentation reports a spindle cell carcinoma of the gingiva and highlights the difficulties encountered in the diagnosis. It also emphasizes the importance of accurate and thorough diagnosis of malignant spindle cell lesions to determine the appropriate therapeutic modality.

Entities:  

Keywords:  Biphasic tumour; Cytokeratin; Spindle cell lesions

Year:  2016        PMID: 27042594      PMCID: PMC4800661          DOI: 10.7860/JCDR/2016/17522.7261

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  6 in total

Review 1.  Squamous cell carcinoma of the upper aerodigestive tract: precursors and problematic variants.

Authors:  Bruce M Wenig
Journal:  Mod Pathol       Date:  2002-03       Impact factor: 7.842

2.  A case of esophageal sarcomatoid carcinoma with molecular evidence of a monoclonal origin.

Authors:  K Kashiwabara; T Sano; T Oyama; T Najahima; F Makita; N Hashimoto; K Iwanami; O Kawashima; T Matsumoto; Y Matsuzaki
Journal:  Pathol Res Pract       Date:  2001       Impact factor: 3.250

3.  Sarcomatoid (spindle cell) carcinoma of the head and neck mucosal region: a clinicopathologic review of 103 cases from a tertiary referral cancer centre.

Authors:  Seethalakshmi Viswanathan; Khaliqur Rahman; Suryawanshi Pallavi; Johari Sachin; Asawari Patil; Pankaj Chaturvedi; Anil D'Cruz; Jaiprakash Agarwal; S V Kane
Journal:  Head Neck Pathol       Date:  2010-08-22

4.  Spindle cell carcinoma of the oral cavity and oropharynx: factors affecting outcome.

Authors:  Hsing-Hao Su; Sau-Tung Chu; Yu-Yi Hou; Kuo-Ping Chang; Chia-Jung Chen
Journal:  J Chin Med Assoc       Date:  2006-10       Impact factor: 2.743

5.  Sarcomatoid carcinoma of the head and neck: molecular evidence for evolution and progression from conventional squamous cell carcinomas.

Authors:  Hong-Ran Choi; Erich M Sturgis; David I Rosenthal; Mario A Luna; John G Batsakis; Adel K El-Naggar
Journal:  Am J Surg Pathol       Date:  2003-09       Impact factor: 6.394

6.  Spindle cell carcinoma of the gingiva: A rare occurrence.

Authors:  Anjana Ramamurti; Madhumathi Venkataraman; Malathi Narasimhan; Suresh Ranga Rao
Journal:  Contemp Clin Dent       Date:  2013-10
  6 in total

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