Literature DB >> 27042583

Clinicopathologic Correlation of White, Non scrapable Oral Mucosal Surface Lesions: A Study of 100 Cases.

Mohammed Abidullah1, Vandana Raghunath2, Tanveer Karpe3, Syed Akifuddin4, Shahid Imran5, Venkata Naga Nalini Dhurjati6, Mohammed Ahtesham Aleem7, Farheen Khatoon8.   

Abstract

INTRODUCTION: White, non scrapable lesions are commonly seen in the oral cavity. Based on their history and clinical appearance, most of these lesions can be easily diagnosed, but sometimes diagnosis may go wrong. In order to arrive to a confirmative diagnosis, histopathological assessment is needed in many cases, if not all. AIMS: 1) To find out the prevalence of clinically diagnosed oral white, non scrapable lesions. 2) To find out the prevalence of histopathologically diagnosed oral white, non scrapable lesions. 3) To correlate the clinical and histopathological diagnosis in the above lesions.
MATERIALS AND METHODS: A total of 100 cases of oral white, non scrapable lesions were included in the study. Based on their history and clinical presentation, clinical provisional diagnosis was made. Then biopsy was done and confirmatory histopathological diagnosis was given and both were correlated. In order to correlate clinical and histopathological diagnosis Discrepancy Index (DI) was calculated for all the cases.
RESULTS: Based on clinical diagnosis, there were 59 cases (59%) of leukoplakia, 29 cases (29%) of lichen planus and six cases (6%) of lichenoid reaction; whereas, based on histopathological diagnosis, there were 66 cases (66%) of leukoplakia epithelial hyperplasia and hyperkeratosis (leukoplakia) and 30 cases (30%) of lichen planus. Seventy eight clinically diagnosed cases (78%) correlated with the histopathological diagnosis and 22 cases (22%) did not correlate. The total discrepancy index was 22%.
CONCLUSION: A clinician needs to be aware of oral white, non scrapable lesions. Due to the overlapping of many clinical features in some of these lesions and also due to their malignant potential, a histopathological confirmative diagnosis is recommended.

Entities:  

Keywords:  Frictional keratosis; Leukoedema; Leukoplakia; Lichen planus; Lichenoid reaction

Year:  2016        PMID: 27042583      PMCID: PMC4800649          DOI: 10.7860/JCDR/2016/16950.7226

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  18 in total

1.  Epidemiological and clinicopathological study of oral leukoplakia.

Authors:  Minati Mishra; Janardan Mohanty; Sujata Sengupta; Satyabrata Tripathy
Journal:  Indian J Dermatol Venereol Leprol       Date:  2005 May-Jun       Impact factor: 2.545

Review 2.  Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation.

Authors:  Sumairi B Ismail; Satish K S Kumar; Rosnah B Zain
Journal:  J Oral Sci       Date:  2007-06       Impact factor: 1.556

3.  Clinicopathologic aspects of oral leukoplakia in smokers and nonsmokers.

Authors:  Marcio Diniz Freitas; Andrés Blanco-Carrión; Pilar Gándara-Vila; José Antúnez-López; Abel García-García; José Manuel Gándara Rey
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2006-04-21

4.  Prevalence study of oral white lesions with special reference to a new definition of oral leucoplakia.

Authors:  K P Schepman; E H van der Meij; L E Smeele; I van der Waal
Journal:  Eur J Cancer B Oral Oncol       Date:  1996-11

5.  Potentially malignant epithelial oral lesions: discrepancies between clinical and histological diagnosis.

Authors:  M A Onofre; M R Sposto; C M Navarro; M E Motta; E Turatti; R T Almeida
Journal:  Oral Dis       Date:  1997-09       Impact factor: 3.511

6.  The prevalence of oral mucosal lesions in the elderly in a surgical biopsy population: a retrospective analysis of 4042 cases.

Authors:  J Scott; S B Cheah
Journal:  Gerodontology       Date:  1989       Impact factor: 2.980

7.  Clinical and histologic study of oral leukoplakia in relation to habits. A five-year follow-up.

Authors:  F S Mehta; D K Daftary; B C Shroff; L D Sanghvi
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1969-09

8.  Oral mucosal lesions in a representative cross-sectional study of aging Germans.

Authors:  P A Reichart
Journal:  Community Dent Oral Epidemiol       Date:  2000-10       Impact factor: 3.383

9.  Epidemiological study of oral leukoplakia based on mass screening for oral mucosal diseases in a selected Japanese population.

Authors:  N Ikeda; T Ishii; S Iida; T Kawai
Journal:  Community Dent Oral Epidemiol       Date:  1991-06       Impact factor: 3.383

10.  Prevalence study of oral mucosal lesions in a selected Cambodian population.

Authors:  N Ikeda; Y Handa; S P Khim; C Durward; T Axéll; T Mizuno; H Fukano; T Kawai
Journal:  Community Dent Oral Epidemiol       Date:  1995-02       Impact factor: 3.383

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  1 in total

1.  Rare Report Case of Oral Verruca Vulgaris on Torus Palatinus.

Authors:  Lee Kian Khoo; Low Eng Chai; Bishwa Prakash Bhattarai; Dinesh Rokaya; Boonaur Yongvanichakorn; Natthamet Wongsirichat
Journal:  Eur J Dent       Date:  2021-10-21
  1 in total

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