Literature DB >> 27042519

Role of Amylase and Lipase Levels in Diagnosis of Blunt Trauma Abdomen.

Ravinder Pal Singh1, Nikhil Garg2, Amandeep S Nar3, Anuj Mahajan2, Atul Mishra4, Jaspal Singh5, Ashish Ahuja1, Ashvind Bawa3.   

Abstract

INTRODUCTION: Blunt Trauma Abdomen (BTA) is the leading cause of morbidity and mortality amongst all age groups. Spectrum of injury may vary from simple to life threatening multi organ involvement and therefore proper assessment and diagnosis becomes very important. AIM: To evaluate the role of serum amylase and lipase in diagnosis of blunt trauma abdomen.
MATERIALS AND METHODS: This study was done on 50 patients with diagnosis of BTA admitted in Dayanand Medical College and Hospital, Ludhiana. Serum amylase and lipase levels were estimated on days 1, 3 and 5 of admission.
RESULTS: Road side accident was the most common aetiology accounting for 40 patients. Thirty one patients were less than 35 years of age and 42 patients were males. Abdominal tenderness was the most common per abdomen finding, found in 31 patients, followed by distension, found in 21 patients. The most common organ injured was liver, seen in 27 patients. Fifteen patients underwent laparotomy while 35 patients were managed conservatively. There was statistically significant rise in serum amylase levels on days 1, 3 and 5 in patients with small and large intestinal injury. There was statistically significant rise in serum lipase levels on days 1, 3 and 5 in patients with stomach injury. Raised levels of serum amylase and lipase had a statistically significant prediction for the need of surgery in these patients.
CONCLUSION: Serum amylase and lipase levels, when coupled with other laboratory tests and imaging modalities, may have significant role in predicting the site of injury as well as the surgical outcome in patients of BTA.

Entities:  

Keywords:  Investigations in trauma; Liver injury; Surgery for trauma

Year:  2016        PMID: 27042519      PMCID: PMC4800585          DOI: 10.7860/JCDR/2016/14346.7308

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  14 in total

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Journal:  Am Surg       Date:  1990-04       Impact factor: 0.688

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Journal:  Ann Surg       Date:  1997-07       Impact factor: 12.969

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8.  Elevated serum pancreatic enzyme levels after hemorrhagic shock predict organ failure and death.

Authors:  Darren J Malinoski; Pantelis Hadjizacharia; Ali Salim; Hubert Kim; Matthew O Dolich; Marianne Cinat; Cristobol Barrios; Michael E Lekawa; David B Hoyt
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Review 9.  Utility of serum pancreatic enzyme levels in diagnosing blunt trauma to the pancreas: a prospective study with systematic review.

Authors:  Abhishek Mahajan; Rajagopal Kadavigere; Smiti Sripathi; Gabriel Sunil Rodrigues; Vedula Rajanikanth Rao; Prakashini Koteshwar
Journal:  Injury       Date:  2014-02-23       Impact factor: 2.586

10.  Evaluation of amylase and lipase levels in blunt trauma abdomen patients.

Authors:  Subodh Kumar; Sushma Sagar; Arulselvi Subramanian; Venencia Albert; Ravindra Mohan Pandey; Nitika Kapoor
Journal:  J Emerg Trauma Shock       Date:  2012-04
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  1 in total

1.  Current Status of Role of Serum Amylase and Lipase to Triage Blunt Pancreatic Trauma?

Authors:  Abhishek Mahajan
Journal:  J Clin Diagn Res       Date:  2016-11-01
  1 in total

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