Literature DB >> 27042502

Primary Spindle Cell Malignant Melanoma of Esophagus: An Unusual Finding.

Nirmalkumar A Rawandale1, Kishor H Suryawanshi2.   

Abstract

Malignant melanoma of esophagus is usually a metastatic tumour rather than a primary tumour. Primary malignant melanoma accounts for less than 0.2% of all esophageal neoplasm. We report a case of primary spindle cell malignant melanoma of esophagus in a 69-year-old male who presented with history of dysphagia since 1 month. Radiological examinations revealed polypoidal growth at lateral aspect of esophagus. Biopsy was reported as grade III squamous cell carcinoma. Video assisted thoracoscopic esophagectomy was performed. Histopathological examination along with immunohistochemistry gave confirmed diagnosis of primary spindle cell malignant melanoma of esophagus. Though a rare entity, due to its aggressive nature and poor prognosis primary malignant melanoma should be one of the differential diagnoses in a patient with polypoidal esophageal mass lesion. Despite radical surgical treatment prognosis is extremely poor.

Entities:  

Keywords:  Malignant; Melanocytes; Polypoidal mass

Year:  2016        PMID: 27042502      PMCID: PMC4800568          DOI: 10.7860/JCDR/2016/16121.7188

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  10 in total

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Journal:  Arch Pathol Lab Med       Date:  2008-10       Impact factor: 5.534

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Authors:  Amy Hoi-Ying Pun; Peter G Devitt
Journal:  J Surg Case Rep       Date:  2014-02-18
  10 in total
  4 in total

1.  Spindle cell carcinoma of the esophagus: A multicenter analysis in comparison with typical squamous cell carcinoma.

Authors:  Baihua Zhang; Qin Xiao; Desong Yang; Xu Li; Jun Hu; Yonggang Wang; Wenxiang Wang
Journal:  Medicine (Baltimore)       Date:  2016-09       Impact factor: 1.889

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Authors:  Ji Li; Yan Liu; Bin Wang; Xun Sun; Xiangwei Meng
Journal:  Medicine (Baltimore)       Date:  2019-03       Impact factor: 1.817

Review 3.  The Thousand Faces of Malignant Melanoma: A Systematic Review of the Primary Malignant Melanoma of the Esophagus.

Authors:  Gerardo Cazzato; Eliano Cascardi; Anna Colagrande; Teresa Lettini; Leonardo Resta; Cinzia Bizzoca; Francesca Arezzo; Vera Loizzi; Miriam Dellino; Gennaro Cormio; Nadia Casatta; Carmelo Lupo; Antonio Scillimati; Salvatore Scacco; Paola Parente; Lucia Lospalluti; Giuseppe Ingravallo
Journal:  Cancers (Basel)       Date:  2022-07-30       Impact factor: 6.575

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Authors:  Zhe Xu; Ping Shi; Feiluore Yibulayin; Lei Feng; Hao Zhang; Alimujiang Wushou
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  4 in total

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