Literature DB >> 27041803

Prescribing for patients on dialysis.

Brendan Smyth1, Ceridwen Jones1, John Saunders1.   

Abstract

The pharmacokinetics of a drug may be altered in patients with renal impairment who require dialysis. Some drugs are contraindicated. The drug's clearance and therapeutic index determine if a dose adjustment is needed. A lower dose or less frequent dosing may be required. Consult a reference source or the patient's nephrologist before prescribing. Start at a low dose and increase gradually. If possible give once-daily drugs after dialysis.

Entities:  

Keywords:  haemodialysis; kidney; pharmacokinetics; renal disease

Year:  2016        PMID: 27041803      PMCID: PMC4816865          DOI: 10.18773/austprescr.2016.008

Source DB:  PubMed          Journal:  Aust Prescr        ISSN: 0312-8008


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