Literature DB >> 27039764

The Neutrophil to Lymphocyte Ratio is an Independent Prognostic Factor in Patients with Metastatic Gastric Cancer.

Fatma Yalcin Musri1, Hasan Mutlu, Melek Karakurt Eryilmaz, Derya Kivrak Salim, Seyda Gunduz, Hasan Senol Coskun.   

Abstract

Inflammation can play an important role in cancer progression and the prognostic importance of neutrophil to lymphocyte ratio (NLR), a marker of inflammation, in cancer is a current investigation topic. In the present study, we aimed to determine whether there is a prognostic link between NLR and metastatic gastric cancer (mGC). A total of 143 patients from the Akdeniz University and Antalya Training and Research Hospital database were retrospectively analyzed. The median NLR value was 3.34. The median overall survival (OS) and median progression-free survival (PFS) were 11.6 and 7.9 months, respectively, in patients with NLR<3.34 while these values were 8.3 and 6.2 months respectively in patients with NLR >3.34 (p<0.001 and p=0.011, respectively). Our study showed that increased NLR is an independent prognostic factor associated with short survival in patients with mGC.

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Year:  2016        PMID: 27039764     DOI: 10.7314/apjcp.2016.17.3.1309

Source DB:  PubMed          Journal:  Asian Pac J Cancer Prev        ISSN: 1513-7368


  4 in total

1.  Pre-treatment Peripheral Neutrophil-Lymphocyte Ratio as a Prognostic Marker in Gastric Cancer.

Authors:  Monika Magdy; Tarek Hussein; Ahmed Ezzat; Ahmed Gaballah
Journal:  J Gastrointest Cancer       Date:  2019-12

2.  The Prognostic Role of the Change in Neutrophil-to-Lymphocyte Ratio During Neoadjuvant Chemotherapy in Patients with Muscle-Invasive Bladder Cancer: A Retrospective, Multi-Institutional Study.

Authors:  Jeenan Kaiser; Haocheng Li; Scott A North; Raya Leibowitz-Amit; Jo-An Seah; Nisha Morshed; Caroline Chau; Richard Lee-Ying; Daniel Y C Heng; Srikala Sridhar; Simon J Crabb; Nimira S Alimohamed
Journal:  Bladder Cancer       Date:  2018-04-26

3.  Clinicopathological and prognostic significance of high circulating lymphocyte ratio in patients receiving neoadjuvant chemotherapy for advanced gastric cancer.

Authors:  Yang Li; Yao Wei; Qi He; Xulin Wang; Chaogang Fan; Guoli Li
Journal:  Sci Rep       Date:  2018-04-18       Impact factor: 4.379

4.  Neutrophil-to-lymphocyte ratio as a predictive or prognostic factor for gastric cancer treated with nivolumab: a multicenter retrospective study.

Authors:  Takatsugu Ogata; Hironaga Satake; Misato Ogata; Yukimasa Hatachi; Kentaro Inoue; Madoka Hamada; Hisateru Yasui
Journal:  Oncotarget       Date:  2018-10-02
  4 in total

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