Literature DB >> 27038794

Post-trauma mortality increase at age 60: a cutoff for defining elderly?

Mackenzie Campbell-Furtick1, Billy J Moore2, Tiffany L Overton2, Jessica Laureano Phillips2, Kaley J Simon2, Rajesh R Gandhi3, Therese M Duane4, Shahid Shafi2.   

Abstract

BACKGROUND: There has been an increasing emphasis on identifying elderly trauma patients. However, definitions based solely on age vary widely, ranging from age 55 to 80 years, hampering optimal trauma management for older patients. The goal of this study was to develop an objective, data-driven definition for "elderly" in trauma care by evaluating mortality risk as a function of age.
METHODS: We conducted a retrospective analysis of 872,861 adult (≥18 years) patients from the National Trauma Data Bank's National Sample Program from 2003 to 2010. The primary outcome was risk-adjusted in-hospital mortality determined using multivariate logistic regression. Contribution of age to mortality was investigated through step-wise regression and percent of R2 attributable to age. We searched for straight-line trends in mortality rate at each age using the spline function of Statistical Analysis Software.
RESULTS: Statistically significant increases in mortality rate were noted at ages 37, 60, and 78. Age was found to contribute 10% to mortality compared with greater than 80% for Glasgow coma scale and injury severity score combined.
CONCLUSIONS: Our findings suggest using age 60 years as a data-driven definition of "elderly" in trauma. Published by Elsevier Inc.

Entities:  

Keywords:  Age cutoff; Elderly age; Elderly trauma; Geriatric trauma; Mortality

Mesh:

Year:  2016        PMID: 27038794     DOI: 10.1016/j.amjsurg.2015.12.018

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  14 in total

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2.  Improvement in geriatric trauma outcomes in an evolving trauma system.

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3.  Mortality Profile of Geriatric Trauma at a Level 1 Trauma Center.

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4.  The elderly age criterion for increased in-hospital mortality in trauma patients: a retrospective cohort study.

Authors:  Ji Hwan Lee; Min Joung Kim; Ju Young Hong; Jinwoo Myung; Yun Ho Roh; Sung Phil Chung
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2021-09-10       Impact factor: 2.953

5.  Short-term outcome following significant trauma: increasing age per se has only a relatively low impact.

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6.  Identification of unique microRNA expression patterns in bone marrow hematopoietic stem and progenitor cells after hemorrhagic shock and multiple injuries in young and old adult mice.

Authors:  Dijoia B Darden; Juan C Mira; Maria-Cecilia Lopez; Julie A Stortz; Brittany P Fenner; Lauren S Kelly; Dina C Nacionales; Ashrita Budharaju; Tyler J Loftus; Henry V Baker; Frederick A Moore; Scott C Brakenridge; Lyle L Moldawer; Alicia M Mohr; Philip A Efron
Journal:  J Trauma Acute Care Surg       Date:  2021-10-01       Impact factor: 3.697

7.  Trauma Early Mortality Prediction Tool (TEMPT) for assessing 28-day mortality.

Authors:  Ryan C Kunitake; Lucy Z Kornblith; Mitchell Jay Cohen; Rachael A Callcut
Journal:  Trauma Surg Acute Care Open       Date:  2018-01-08

8.  Impact of comorbidities on the prognoses of trauma patients: Analysis of a hospital-based trauma registry database.

Authors:  Chih-Yuan Wang; Yi-Chan Chen; Ti-Hsuan Chien; Hao-Yu Chang; Yu-Hsien Chen; Chih-Ying Chien; Ting-Shuo Huang
Journal:  PLoS One       Date:  2018-03-20       Impact factor: 3.240

9.  Association between prehospital time and outcome of trauma patients in 4 Asian countries: A cross-national, multicenter cohort study.

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Review 10.  Challenges in the PREHOSPITAL emergency management of geriatric trauma patients - a scoping review.

Authors:  Michael Eichinger; Henry Douglas Pow Robb; Cosmo Scurr; Harriet Tucker; Stefan Heschl; George Peck
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2021-07-23       Impact factor: 2.953

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