J Limeres1, J F Garcez2, J S Marinho3, A Loureiro4, M Diniz1, P Diz1. 1. Special Needs Unit and OMEQUI Research Group, School of Medicine and Dentistry, Santiago de Compostela University, Santiago de Compostela, Spain. 2. Instituto Superior de Ciências da Saúde-Norte (ISCS-N), Gandra, Portugal. 3. Stomatology Department. Instituto Portugués de Oncología Francisco Gentil (IPO), Porto, Portugal. 4. Nephrology Department. Instituto Portugués de Oncología Francisco Gentil (IPO), Porto, Portugal.
Abstract
OBJECTIVE: This article sets out to evaluate the prevalence and aetiopathogenesis of edentulism in patients on haemodialysis. SUBJECTS AND METHODS: The study group comprised 44 adult patients with end-stage renal disease (ESRD) on haemodialysis. A control group was formed of 44 individuals matched for age and sex and with a glomerular filtration rate >90 ml min(-1) . All participants underwent intra-oral examination, gathering information on dental and periodontal status, and a saliva sample was taken to determine saliva debit and its biochemical composition. RESULTS: The average number of missing teeth was higher in ESRD patients than in controls (P = 0.018). Six (13.6%) fully edentulous individuals were detected in the study group and 1 (2.2%) in the control group. Some of the clinical and biochemical variables with statistically significant differences between the study group and the control group showed a significant relationship with the number of missing teeth, but the depth of the periodontal pockets presented the highest coefficient of determination (OR = 3511.1; 95%CI = 82.2-6834.3; P < 0.001; R(2) = 0.827). CONCLUSIONS: Premature tooth loss is common in haemodialysis patients. Although the aetiology and pathogenesis of this finding has still not been fully clarified, it appears that severe periodontal disease may play a relevant role.
OBJECTIVE: This article sets out to evaluate the prevalence and aetiopathogenesis of edentulism in patients on haemodialysis. SUBJECTS AND METHODS: The study group comprised 44 adult patients with end-stage renal disease (ESRD) on haemodialysis. A control group was formed of 44 individuals matched for age and sex and with a glomerular filtration rate >90 ml min(-1) . All participants underwent intra-oral examination, gathering information on dental and periodontal status, and a saliva sample was taken to determine saliva debit and its biochemical composition. RESULTS: The average number of missing teeth was higher in ESRDpatients than in controls (P = 0.018). Six (13.6%) fully edentulous individuals were detected in the study group and 1 (2.2%) in the control group. Some of the clinical and biochemical variables with statistically significant differences between the study group and the control group showed a significant relationship with the number of missing teeth, but the depth of the periodontal pockets presented the highest coefficient of determination (OR = 3511.1; 95%CI = 82.2-6834.3; P < 0.001; R(2) = 0.827). CONCLUSIONS:Premature tooth loss is common in haemodialysis patients. Although the aetiology and pathogenesis of this finding has still not been fully clarified, it appears that severe periodontal disease may play a relevant role.
Authors: Quan Yuan; Qiu-Chan Xiong; Megha Gupta; Rosa María López-Pintor; Xiao-Lei Chen; Dutmanee Seriwatanachai; Michael Densmore; Yi Man; Ping Gong Journal: Int J Oral Sci Date: 2017-06-23 Impact factor: 6.344