Literature DB >> 27037395

Lesson of the month 1: Splinter haemorrhages as a pointer to gastrointestinal malignancy.

Cositha Santhamkumar1, Chantal Faddoul1, Russell Barker2, Rochelle Facer1, Sandhya Limaye3.   

Abstract

A 58-year-old man was referred for review due to the finding of splinter haemorrhages and digital infarcts. Further questioning revealed a history of unintentional weight loss and calf pain. There were no other clinical features of endocarditis, and no clear cause for the splinter haemorrhages on initial investigations. The discovery of widespread thromboembolic disease prompted a search for malignancy and an eventual diagnosis of oesophageal adenocarcinoma. Splinter haemorrhages resolved with anticoagulation and directed treatment of the underlying malignancy. This case report reminds clinicians of the potentially broad differential diagnosis associated with this clinical sign.
© 2016 Royal College of Physicians.

Entities:  

Keywords:  Splinter haemorrhage; chemotherapy; clinical examination; hypercoaguability; malignancy; oesophageal ­adenocarcinoma

Mesh:

Substances:

Year:  2016        PMID: 27037395      PMCID: PMC4952979          DOI: 10.7861/clinmedicine.16-2-199

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  6 in total

1.  CLINICAL SIGNIFICANCE OF SPLINTER HAEMORRHAGES.

Authors:  N J GROSS; R TALL
Journal:  Br Med J       Date:  1963-12-14

2.  Splinter haemorrhages associated with oral terbinafine in a Chinese man.

Authors:  Cheng Tan; Wen-Yuan Zhu
Journal:  Clin Exp Dermatol       Date:  2006-01       Impact factor: 3.470

3.  Recurrent splinter haemorrhages weeks after a tick bite.

Authors:  T S van der Werf; J E Tulleken; J G Zijlstra
Journal:  Neth J Med       Date:  2004 Jul-Aug       Impact factor: 1.422

4.  Prolonged fever and splinter hemorrhages in an immunocompetent traveler with disseminated histoplasmosis.

Authors:  Roni Bitterman; Ilana Oren; Yuval Geffen; Hannah Sprecher; Eli Schwartz; Ami Neuberger
Journal:  J Travel Med       Date:  2013 Jan-Feb       Impact factor: 8.490

5.  Nail changes in connective tissue diseases: do nail changes provide clues for the diagnosis?

Authors:  S E Tunc; I Ertam; T Pirildar; T Turk; M Ozturk; E Doganavsargil
Journal:  J Eur Acad Dermatol Venereol       Date:  2007-04       Impact factor: 6.166

Review 6.  Nail abnormalities: clues to systemic disease.

Authors:  Robert S Fawcett; Sean Linford; Daniel L Stulberg
Journal:  Am Fam Physician       Date:  2004-03-15       Impact factor: 3.292

  6 in total

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