| Literature DB >> 27037395 |
Cositha Santhamkumar1, Chantal Faddoul1, Russell Barker2, Rochelle Facer1, Sandhya Limaye3.
Abstract
A 58-year-old man was referred for review due to the finding of splinter haemorrhages and digital infarcts. Further questioning revealed a history of unintentional weight loss and calf pain. There were no other clinical features of endocarditis, and no clear cause for the splinter haemorrhages on initial investigations. The discovery of widespread thromboembolic disease prompted a search for malignancy and an eventual diagnosis of oesophageal adenocarcinoma. Splinter haemorrhages resolved with anticoagulation and directed treatment of the underlying malignancy. This case report reminds clinicians of the potentially broad differential diagnosis associated with this clinical sign.Entities:
Keywords: Splinter haemorrhage; chemotherapy; clinical examination; hypercoaguability; malignancy; oesophageal adenocarcinoma
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Year: 2016 PMID: 27037395 PMCID: PMC4952979 DOI: 10.7861/clinmedicine.16-2-199
Source DB: PubMed Journal: Clin Med (Lond) ISSN: 1470-2118 Impact factor: 2.659