Literature DB >> 27037251

Is Expanded HIV Testing Associated with Earlier HIV Diagnosis? Results from an HIV Clinic in Guatemala City.

Alisha Liggett1, Narda Medina2, Blanca Samayoa3, Danicela Mercado2, Mirna Castillo2, Erwin Argueta2, Miguel Anderson4, Matthew Anderson4, Eduardo Arathoon2.   

Abstract

BACKGROUND: Most patients in Guatemala are diagnosed with advanced HIV disease. Patients that present late in the disease process may miss the morbidity and mortality benefits associated with early treatment and may unknowingly spread HIV to others. RESEARCH QUESTIONS: We examined trends in HIV detection and levels of immunosuppression at diagnosis from 2005 -2012 to determine if expanded HIV testing was associated with earlier detection of HIV.
SETTING: This study was conducted at the Clínica Familiar Luis Ángel García (CFLAG), a major HIV center associated with one of Guatemala's two national hospitals. HIV testing expanded rapidly after 2007 due to grants from the Global Fund which allowed for routine prenatal testing.
METHODS: This study examined existing hospital and clinic databases from to evaluate results from HIV tests performed, and baseline CD4 cells/mm(3) on all patients newly diagnosed with HIV infection from 2005 to 2012.
RESULTS: We found a decline in the number of HIV positive tests over the study period despite an increase in the total number of tests performed. Sixty-two percent of HIV infected individuals had AIDS at diagnosis. We observed a decrease in median CD4 cells/mm(3) among the prenatal testees and no change in non-prenatal testees. DISCUSSION: Expanded HIV counseling and testing services in our clinic did not result in earlier HIV diagnosis.
© The Author(s) 2016.

Entities:  

Keywords:  AIDS; CFLAG; HIV; immunosuppression; median CD4

Mesh:

Year:  2016        PMID: 27037251     DOI: 10.1177/2325957416640362

Source DB:  PubMed          Journal:  J Int Assoc Provid AIDS Care        ISSN: 2325-9574


  2 in total

1.  Late Presentation and Missed Opportunities for HIV Diagnosis in Guatemala.

Authors:  Johanna Meléndez; Samuel W Reinhardt; Jane A O'Halloran; Andrej Spec; Andrea Alonzo Cordon; William G Powderly; Carlos Mejia Villatoro
Journal:  AIDS Behav       Date:  2019-04

2.  Global Trends in CD4 Cell Count at the Start of Antiretroviral Therapy: Collaborative Study of Treatment Programs.

Authors: 
Journal:  Clin Infect Dis       Date:  2018-03-05       Impact factor: 9.079

  2 in total

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