Literature DB >> 27036887

An unusual presentation of primary hyperparathyroidism: multiple brown tumors and coexisting thyroid carcinoma.

Y Basaran1, S Ince2, E Alagoz3, C Meric1, A Taslipinar1.   

Abstract

We present a patient with a complex clinical picture of primary hyperparathyroidism with multiple destructive skeletal lesions suspicious of bone metastases and concomitant multifocal papillary thyroid carcinoma with a metastatic central lymph node. He presented with progressively worsening right hip pain and restricted motion. Magnetic resonance imaging revealed multiple lytic lesions involving predominantly the right trochanter minor and the left inferior and posterior pubic rami. Biochemical tests were consistent with primary hyperparathyroidism. Neck ultrasound and parathyroid scintigraphy revealed a single parathyroid adenoma and a thyroid nodule, preoperative cytology of which confirmed papillary thyroid carcinoma, as did the final surgical specimen. Biochemical results, regarding hyperparathyroidism, declined to normal levels and his complaints gradually decreased after surgery. Postoperative whole body bone scintigraphy showed increased tracer uptakes at multiple sites, but they were proved to be metabolically inactive by fluorodeoxyglucose positron emission tomography/computed tomography.
Copyright © 2016 Elsevier España, S.L.U. y SEMNIM. All rights reserved.

Entities:  

Keywords:  Adenoma paratiroideo; Bone scintigraphy; Brown tumor; FDG PET/CT; FDG PET/TC; Gammagrafía ósea; Parathyroid adenoma; Tumor pardo

Mesh:

Year:  2016        PMID: 27036887     DOI: 10.1016/j.remn.2016.02.005

Source DB:  PubMed          Journal:  Rev Esp Med Nucl Imagen Mol        ISSN: 2253-654X            Impact factor:   1.359


  2 in total

1.  Multiple bone brown tumor secondary to primary hyperparathyroidism: a case report and literature review.

Authors:  Weibo Xu; Yanqing Qu; Wen Shi; Ben Ma; Hongyi Jiang; Yu Wang; Ning Qu; Yongxue Zhu
Journal:  Gland Surg       Date:  2019-12

Review 2.  Is there a consensus between clinical practice guidelines for conventional and molecular nuclear medicine studies in parathyroid pathology?

Authors:  Marylin Acuña Hernandez; Liset Sanchez Orduz; Uvi Cancino Ramos; Paola Vallejo Armenta; Leonardo Cadavid Blanco
Journal:  Ann Nucl Med       Date:  2021-07-24       Impact factor: 2.668

  2 in total

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