Literature DB >> 27036162

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia.

Anna Wojtuszkiewicz1, Yehuda G Assaraf2, Mirthe Hoekstra3, Rocco Sciarrillo4, Gerrit Jansen5, Godefridus J Peters6, Rob Pieters7, Edwin Sonneveld8, Gabriele Escherich9, Gertjan J L Kaspers3, Jacqueline Cloos10.   

Abstract

Entities:  

Keywords:  aberrant splicing; dexamethasone; folylpolyglutamate synthetase; methotrexate; pediatric acute lymphoblastic leukemia

Mesh：

Substances：

Year:  2016        PMID： 27036162      PMCID： PMC5004475          DOI： 10.3324/haematol.2016.142794

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  14 in total

1.  Cooperative study group for childhood acute lymphoblastic leukaemia (COALL): long-term results of trials 82,85,89,92 and 97.

Authors:  G Escherich; M A Horstmann; M Zimmermann; G E Janka-Schaub
Journal:  Leukemia       Date:  2009-12-17       Impact factor: 11.528

2.  Long-term results of Dutch Childhood Oncology Group studies for children with acute lymphoblastic leukemia from 1984 to 2004.

Authors:  W A Kamps; K M van der Pal-de Bruin; A J P Veerman; M Fiocco; M Bierings; R Pieters
Journal:  Leukemia       Date:  2009-12-17       Impact factor: 11.528

3.  mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method.

Authors:  M G Rots; J C Willey; G Jansen; C H Van Zantwijk; P Noordhuis; J P DeMuth; E Kuiper; A J Veerman; R Pieters; G J Peters
Journal:  Leukemia       Date:  2000-12       Impact factor: 11.528

Review 4.  Molecular basis of antifolate resistance.

Authors:  Yehuda G Assaraf
Journal:  Cancer Metastasis Rev       Date:  2007-03       Impact factor: 9.264

5.  Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia.

Authors:  M G Rots; R Pieters; G J Peters; P Noordhuis; C H van Zantwijk; G J Kaspers; K Hählen; U Creutzig; A J Veerman; G Jansen
Journal:  Blood       Date:  1999-03-01       Impact factor: 22.113

Review 6.  Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance.

Authors:  Anna Wojtuszkiewicz; Yehuda G Assaraf; Marielle J P Maas; Gertjan J L Kaspers; Gerrit Jansen; Jacqueline Cloos
Journal:  Expert Opin Drug Metab Toxicol       Date:  2014-12-13       Impact factor: 4.481

7.  Aberrant splicing of folylpolyglutamate synthetase as a novel mechanism of antifolate resistance in leukemia.

Authors:  Michal Stark; Chen Wichman; Irit Avivi; Yehuda G Assaraf
Journal:  Blood       Date:  2009-01-08       Impact factor: 22.113

8.  Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.

Authors:  E Masson; M V Relling; T W Synold; Q Liu; J D Schuetz; J T Sandlund; C H Pui; W E Evans
Journal:  J Clin Invest       Date:  1996-01-01       Impact factor: 14.808

9.  Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance.

Authors:  Anna Wojtuszkiewicz; Shachar Raz; Michal Stark; Yehuda G Assaraf; Gerrit Jansen; Godefridus J Peters; Edwin Sonneveld; Gertjan J L Kaspers; Jacqueline Cloos
Journal:  Int J Cancer       Date:  2015-11-25       Impact factor: 7.396

10.  Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.

Authors:  Anna Wojtuszkiewicz; Godefridus J Peters; Nicole L van Woerden; Boas Dubbelman; Gabriele Escherich; Kjeld Schmiegelow; Edwin Sonneveld; Rob Pieters; Peter M van de Ven; Gerrit Jansen; Yehuda G Assaraf; Gertjan J L Kaspers; Jacqueline Cloos
Journal:  J Hematol Oncol       Date:  2015-05-29       Impact factor: 17.388
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  4 in total

1.  Association of altered folylpolyglutamate synthetase pre-mRNA splicing with methotrexate unresponsiveness in early rheumatoid arthritis.

Authors:  Ittai B Muller; Marry Lin; Willem F Lems; Marieke M Ter Wee; Anna Wojtuszkiewicz; Michael T Nurmohamed; Jacqueline Cloos; Yehuda G Assaraf; Gerrit Jansen; Robert de Jonge
Journal:  Rheumatology (Oxford)       Date:  2021-03-02       Impact factor: 7.580

2.  Computational comparison of common event-based differential splicing tools: practical considerations for laboratory researchers.

Authors:  Ittai B Muller; Stijn Meijers; Peter Kampstra; Steven van Dijk; Michel van Elswijk; Marry Lin; Anna M Wojtuszkiewicz; Gerrit Jansen; Robert de Jonge; Jacqueline Cloos
Journal:  BMC Bioinformatics       Date:  2021-06-26       Impact factor: 3.169

3.  FPGS relapse-specific mutations in relapsed childhood acute lymphoblastic leukemia.

Authors:  Sung-Liang Yu; Hui Zhang; Bing-Ching Ho; Chih-Hsiang Yu; Chia-Ching Chang; Yin-Chen Hsu; Yu-Ling Ni; Kai-Hsin Lin; Shiann-Tarng Jou; Meng-Yao Lu; Shu-Huey Chen; Kang-Hsi Wu; Shih-Chung Wang; Hsiu-Hao Chang; Ching-Hon Pui; Jun J Yang; Jinghui Zhang; Dong-Tsamn Lin; Shu-Wha Lin; Xiaotu Ma; Yung-Li Yang
Journal:  Sci Rep       Date:  2020-07-21       Impact factor: 4.379

Review 4.  Alternative RNA Splicing-The Trojan Horse of Cancer Cells in Chemotherapy.

Authors:  Nikolay Mehterov; Maria Kazakova; Yordan Sbirkov; Boyan Vladimirov; Nikolay Belev; Galina Yaneva; Krassimira Todorova; Soren Hayrabedyan; Victoria Sarafian
Journal:  Genes (Basel)       Date:  2021-07-18       Impact factor: 4.096
  4 in total

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