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Literature DB >> 27036090

Development and function of tissue resident macrophages in mice.

Katrin Kierdorf¹, Marco Prinz², Frederic Geissmann³, Elisa Gomez Perdiguero⁴.

Abstract

Macrophages are important for tissue development, homeostasis as well as immune response upon injury or infection. For a long time they were only seen as one uniform group of phagocytes with a common origin and similar functions. However, this view has been challenged in the last decade and revealed a complex diversity of tissue resident macrophages. Here, we want to present the current view on macrophage development and tissue specification and we will discuss differences as well as common patterns between heterogeneous macrophage subpopulations.

Entities: CellLine Chemical Disease Gene Species

Keywords: Erythro-myeloid progenitor; Macrophage; Mononuclear phagocytes; Pulse labeling models; Tissue specification

Mesh：

Year: 2016 PMID： 27036090 PMCID： PMC4948121 DOI： 10.1016/j.smim.2016.03.017

Source DB: PubMed Journal: Semin Immunol ISSN： 1044-5323 Impact factor: 11.130

131 in total

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36 in total

Review 1. Myeloid Cells in the Central Nervous System.

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Journal: Sci Immunol Date: 2020-03-27