Literature DB >> 27035800

Stereoselective α-Hydroxylation of Amides Using Oppolzer's Sultam as Chiral Auxiliary.

Lumin Zhang1, Lili Zhu1, Jun Yang1, Jisheng Luo1, Ran Hong1.   

Abstract

An Oppolzer's sultam-based highly stereoselective α-hydroxylation of amides was developed to deliver the desired products in good yield and excellent diastereoselectivity (>20/1). The generally crystalline products and the recyclability of the chiral auxiliary illustrate the practicability and scalability of the current approach.

Entities:  

Year:  2016        PMID： 27035800     DOI： 10.1021/acs.joc.6b00068

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Copper-Catalyzed Vinylogous Aerobic Oxidation of Unsaturated Compounds with Air.

Authors:  Hai-Jun Zhang; Alexander W Schuppe; Shi-Tao Pan; Jin-Xiang Chen; Bo-Ran Wang; Timothy R Newhouse; Liang Yin
Journal:  J Am Chem Soc       Date:  2018-04-09       Impact factor: 15.419

Review 2.  Chiral phase-transfer catalysis in the asymmetric α-heterofunctionalization of prochiral nucleophiles.

Authors:  Johannes Schörgenhumer; Maximilian Tiffner; Mario Waser
Journal:  Beilstein J Org Chem       Date:  2017-08-22       Impact factor: 2.883

3.  Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy.

Authors:  Hong-Li Zhang; Zhi-Feng Sun; Lu-Nan Zhou; Lu Liu; Tao Zhang; Zhen-Ting Du
Journal:  Molecules       Date:  2018-06-04       Impact factor: 4.411
  3 in total

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