Literature DB >> 27035067

Ivacaftor-Induced Proteomic Changes Suggest Monocyte Defects May Contribute to the Pathogenesis of Cystic Fibrosis.

Katherine B Hisert1, Kelly Q Schoenfelt2, Gordon Cooke3, Brenda Grogan4, Jan L Launspach5, Charles G Gallagher3,4, Seamas C Donnelly6, Michael J Welsh5, Pradeep K Singh1, Edward F McKone3,4, Lev Becker2.   

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Year:  2016        PMID： 27035067      PMCID： PMC4821059          DOI： 10.1165/rcmb.2015-0322LE

Source DB:  PubMed          Journal:  Am J Respir Cell Mol Biol        ISSN： 1044-1549            Impact factor:   6.914


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  14 in total

Review 1.  Endotoxin tolerance: new mechanisms, molecules and clinical significance.

Authors:  Subhra K Biswas; Eduardo Lopez-Collazo
Journal:  Trends Immunol       Date:  2009-09-24       Impact factor: 16.687

2.  A CFTR potentiator in patients with cystic fibrosis and the G551D mutation.

Authors:  Bonnie W Ramsey; Jane Davies; N Gerard McElvaney; Elizabeth Tullis; Scott C Bell; Pavel Dřevínek; Matthias Griese; Edward F McKone; Claire E Wainwright; Michael W Konstan; Richard Moss; Felix Ratjen; Isabelle Sermet-Gaudelus; Steven M Rowe; Qunming Dong; Sally Rodriguez; Karl Yen; Claudia Ordoñez; J Stuart Elborn
Journal:  N Engl J Med       Date:  2011-11-03       Impact factor: 91.245

3.  Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Authors:  Aravind Subramanian; Pablo Tamayo; Vamsi K Mootha; Sayan Mukherjee; Benjamin L Ebert; Michael A Gillette; Amanda Paulovich; Scott L Pomeroy; Todd R Golub; Eric S Lander; Jill P Mesirov
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-30       Impact factor: 11.205

4.  CFTR regulates phagosome acidification in macrophages and alters bactericidal activity.

Authors:  Anke Di; Mary E Brown; Ludmila V Deriy; Chunying Li; Frances L Szeto; Yimei Chen; Ping Huang; Jiankun Tong; Anjaparavanda P Naren; Vytautas Bindokas; H Clive Palfrey; Deborah J Nelson
Journal:  Nat Cell Biol       Date:  2006-08-20       Impact factor: 28.824

5.  Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis.

Authors:  Emanuela M Bruscia; Ping-Xia Zhang; Ayano Satoh; Christina Caputo; Ruslan Medzhitov; Ambika Shenoy; Marie E Egan; Diane S Krause
Journal:  J Immunol       Date:  2011-05-18       Impact factor: 5.422

6.  Dysfunctional CFTR alters the bactericidal activity of human macrophages against Pseudomonas aeruginosa.

Authors:  Paola Del Porto; Noemi Cifani; Simone Guarnieri; Enea Gino Di Domenico; Maria A Mariggiò; Francesca Spadaro; Silvia Guglietta; Marco Anile; Federico Venuta; Serena Quattrucci; Fiorentina Ascenzioni
Journal:  PLoS One       Date:  2011-05-18       Impact factor: 3.240

7.  IFN-gamma and STAT1 arrest monocyte migration and modulate RAC/CDC42 pathways.

Authors:  Yang Hu; Xiaoyu Hu; Laurence Boumsell; Lionel B Ivashkiv
Journal:  J Immunol       Date:  2008-06-15       Impact factor: 5.422

8.  Cystic fibrosis transmembrane conductance regulator-independent phagosomal acidification in macrophages.

Authors:  Peter M Haggie; A S Verkman
Journal:  J Biol Chem       Date:  2007-08-27       Impact factor: 5.157

Review 9.  Interferon-gamma: an overview of signals, mechanisms and functions.

Authors:  Kate Schroder; Paul J Hertzog; Timothy Ravasi; David A Hume
Journal:  J Leukoc Biol       Date:  2003-10-02       Impact factor: 4.962

10.  Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis.

Authors:  Claudio Sorio; Mario Buffelli; Chiara Angiari; Michele Ettorre; Jan Johansson; Marzia Vezzalini; Laura Viviani; Mario Ricciardi; Genny Verzè; Baroukh Maurice Assael; Paola Melotti
Journal:  PLoS One       Date:  2011-07-21       Impact factor: 3.240
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  19 in total

1.  Lumacaftor (VX-809) restores the ability of CF macrophages to phagocytose and kill Pseudomonas aeruginosa.

Authors:  Roxanna Barnaby; Katja Koeppen; Amanda Nymon; Thomas H Hampton; Brent Berwin; Alix Ashare; Bruce A Stanton
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2017-11-16       Impact factor: 5.464

2.  Acute administration of ivacaftor to people with cystic fibrosis and a G551D-CFTR mutation reveals smooth muscle abnormalities.

Authors:  Ryan J Adam; Katherine B Hisert; Jonathan D Dodd; Brenda Grogan; Janice L Launspach; Janel K Barnes; Charles G Gallagher; Jered P Sieren; Thomas J Gross; Anthony J Fischer; Joseph E Cavanaugh; Eric A Hoffman; Pradeep K Singh; Michael J Welsh; Edward F McKone; David A Stoltz
Journal:  JCI Insight       Date:  2016-04-07

3.  Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections.

Authors:  Katherine B Hisert; Sonya L Heltshe; Christopher Pope; Peter Jorth; Xia Wu; Rachael M Edwards; Matthew Radey; Frank J Accurso; Daniel J Wolter; Gordon Cooke; Ryan J Adam; Suzanne Carter; Brenda Grogan; Janice L Launspach; Seamas C Donnelly; Charles G Gallagher; James E Bruce; David A Stoltz; Michael J Welsh; Lucas R Hoffman; Edward F McKone; Pradeep K Singh
Journal:  Am J Respir Crit Care Med       Date:  2017-06-15       Impact factor: 21.405

Review 4.  Cystic Fibrosis Lung Immunity: The Role of the Macrophage.

Authors:  Emanuela M Bruscia; Tracey L Bonfield
Journal:  J Innate Immun       Date:  2016-06-24       Impact factor: 7.349

5.  Ivacaftor partially corrects airway inflammation in a humanized G551D rat.

Authors:  Morgan Green; Natalie Lindgren; Alexander Henderson; Johnathan D Keith; Ashley M Oden; Susan E Birket
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2021-04-07       Impact factor: 6.011

Review 6.  β2 integrin activation and signal transduction in leukocyte recruitment.

Authors:  Hao Sun; Liang Hu; Zhichao Fan
Journal:  Am J Physiol Cell Physiol       Date:  2021-06-16       Impact factor: 5.282

7.  Inflammatory cytokines TNF-α and IL-17 enhance the efficacy of cystic fibrosis transmembrane conductance regulator modulators.

Authors:  Tayyab Rehman; Philip H Karp; Ping Tan; Brian J Goodell; Alejandro A Pezzulo; Andrew L Thurman; Ian M Thornell; Samantha L Durfey; Michael E Duffey; David A Stoltz; Edward F McKone; Pradeep K Singh; Michael J Welsh
Journal:  J Clin Invest       Date:  2021-08-16       Impact factor: 19.456

8.  Ivacaftor-induced sweat chloride reductions correlate with increases in airway surface liquid pH in cystic fibrosis.

Authors:  Mahmoud H Abou Alaiwa; Jan L Launspach; Brenda Grogan; Suzanne Carter; Joseph Zabner; David A Stoltz; Pradeep K Singh; Edward F McKone; Michael J Welsh
Journal:  JCI Insight       Date:  2018-08-09

9.  Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis.

Authors:  Robert D Gray; Gareth Hardisty; Kate H Regan; Maeve Smith; Calum T Robb; Rodger Duffin; Annie Mackellar; Jennifer M Felton; Lily Paemka; Brian N McCullagh; Christopher D Lucas; David A Dorward; Edward F McKone; Gordon Cooke; Seamas C Donnelly; Pradeep K Singh; David A Stoltz; Christopher Haslett; Paul B McCray; Moira K B Whyte; Adriano G Rossi; Donald J Davidson
Journal:  Thorax       Date:  2017-09-15       Impact factor: 9.139

10.  Ezrin links CFTR to TLR4 signaling to orchestrate anti-bacterial immune response in macrophages.

Authors:  Caterina Di Pietro; Ping-Xia Zhang; Timothy K O'Rourke; Thomas S Murray; Lin Wang; Clemente J Britto; Jonathan L Koff; Diane S Krause; Marie E Egan; Emanuela M Bruscia
Journal:  Sci Rep       Date:  2017-09-07       Impact factor: 4.379
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