Literature DB >> 27034576

Linezolid-induced serotonin toxicity in a patient not taking monoamine oxidase inhibitors or serotonin receptor antagonists.

Jacob Sutton1, Jeff Stroup1, Mo Som1.   

Abstract

Linezolid is an oxazolidinone antibiotic with weak monoamine oxidase (MAO) type A and MAO type B inhibitory effects. Linezolid has been associated with serotonin toxicity when used concomitantly with multiple medications that are known to increase serotonin concentrations. We report the case of a 65-year-old woman with signs and symptoms of serotonin toxicity following administration of linezolid for treatment of methicillin-resistant Staphylococcus aureus pneumonia.

Entities:  

Year:  2016        PMID： 27034576      PMCID： PMC4790578          DOI： 10.1080/08998280.2016.11929423

Source DB:  PubMed          Journal:  Proc (Bayl Univ Med Cent)        ISSN： 0899-8280


  9 in total

1.  The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity.

Authors:  E J C Dunkley; G K Isbister; D Sibbritt; A H Dawson; I M Whyte
Journal:  QJM       Date:  2003-09

2.  Serotonin syndrome due to co-administration of linezolid and venlafaxine.

Authors:  Stephanie Lisa Jones; Eugene Athan; Daniel O'Brien
Journal:  J Antimicrob Chemother       Date:  2004-05-12       Impact factor: 5.790

Review 3.  The serotonin syndrome.

Authors:  Edward W Boyer; Michael Shannon
Journal:  N Engl J Med       Date:  2005-03-17       Impact factor: 91.245

4.  Linezolid-associated serotonin syndrome after concomitant treatment with citalopram and mirtazepine in a critically ill bone marrow transplant recipient.

Authors:  Ronald J DeBellis; Oren P Schaefer; Michelina Liquori; Gregory A Volturo
Journal:  J Intensive Care Med       Date:  2005 Nov-Dec       Impact factor: 3.510

Review 5.  Serotonin toxicity associated with the use of linezolid: a review of postmarketing data.

Authors:  Kenneth R Lawrence; May Adra; P Ken Gillman
Journal:  Clin Infect Dis       Date:  2006-04-27       Impact factor: 9.079

6.  Treatment of the serotonin syndrome with cyproheptadine.

Authors:  A Graudins; A Stearman; B Chan
Journal:  J Emerg Med       Date:  1998 Jul-Aug       Impact factor: 1.484

Review 7.  Oxazolidinones: activity, mode of action, and mechanism of resistance.

Authors:  Bülent Bozdogan; Peter C Appelbaum
Journal:  Int J Antimicrob Agents       Date:  2004-02       Impact factor: 5.283

Review 8.  Clinical pharmacokinetics of linezolid, a novel oxazolidinone antibacterial.

Authors:  Dennis J Stalker; Gail L Jungbluth
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

Review 9.  Clinical pharmacology of MAO inhibitors: safety and future.

Authors:  Mitsuhiko Yamada; Hajime Yasuhara
Journal:  Neurotoxicology       Date:  2004-01       Impact factor: 4.294
  9 in total
  2 in total

1.  Neurological and Psychiatric Adverse Effects of Antimicrobials.

Authors:  Madison K Bangert; Rodrigo Hasbun
Journal:  CNS Drugs       Date:  2019-08       Impact factor: 5.749

Review 2.  Parathyroid Disease in Pregnancy and Lactation: A Narrative Review of the Literature.

Authors:  Elena Tsourdi; Athanasios D Anastasilakis
Journal:  Biomedicines       Date:  2021-04-26
  2 in total

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