| Literature DB >> 27033307 |
Abstract
Tumor microenvironment is involved in the pathogenesis and progression of human lymphomas. The lymphoma microenvironment is composed by stromal cells, immune cells (macrophages, plasma cells, mast cells, eosinophils, basophils, T- and B-cells), blood vessels and extracellular matrix proteins. This article is focused on the role of mast cells in lymphoma progression and angiogenesis. Mast cells might be regarded in a future perspective as a new target for the adjuvant treatment of tumors, including lymphomas.Entities:
Keywords: Angiogenesis; Lymphoma; Mast cells; Tumor microenvironment; Tumor progression
Mesh:
Year: 2016 PMID: 27033307 DOI: 10.1016/j.critrevonc.2016.03.016
Source DB: PubMed Journal: Crit Rev Oncol Hematol ISSN: 1040-8428 Impact factor: 6.312