Literature DB >> 27033296

Cervical vertebral actinomycosis mimicking malignancy in a paediatric patient.

Shyam Prajapati1, Daniel J Yoon2, Carlos L Benitez2, Arzu Buyuk1.   

Abstract

Actinomyces spp are found in the flora of the oral cavity and vagina and may cause infection with abscess formation and draining sinuses. Cervicofacial manifestations of actinomycosis involve head and neck soft tissue, however, spread to the cervical spine is rare. We report a case of an 8-year-old boy, presenting with neck pain for 1 month and denying a history of trauma or procedures. Radiography revealed an ulceration of the posterior oropharyngeal mucosa with a defect extending to the C1-C2 vertebra, mimicking a neoplastic process. The patient underwent laryngoscopy and multiple biopsies were taken from the ulcer and bone, showing severe osteomyelitis and intraosseous filamentous organisms, morphologically consistent with Actinomyces spp. The boy received long-term antibiotics with response to treatment. Actinomycosis has rarely been reported in the cervical vertebrae of paediatric patients. This should be considered as a differential diagnosis for such a presentation as prompt antibiotic treatment may be lifesaving. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID: 27033296      PMCID: PMC4840670          DOI: 10.1136/bcr-2016-214757

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

1.  Cervical spinal cord compression in a child with cervicofacial actinomycosis.

Authors:  Po-Cheng Hung; Huei-Shyong Wang; Cheng-Hsun Chiu; Alex M-C Wong
Journal:  Brain Dev       Date:  2013-08-28       Impact factor: 1.961

Review 2.  MR imaging assessment of the spine: infection or an imitation?

Authors:  Sung Hwan Hong; Ja-Young Choi; Joon Woo Lee; Na Ra Kim; Jung-Ah Choi; Heung Sik Kang
Journal:  Radiographics       Date:  2009 Mar-Apr       Impact factor: 5.333

3.  Atypical presentations of actinomycosis.

Authors:  M J Belmont; P M Behar; M K Wax
Journal:  Head Neck       Date:  1999-05       Impact factor: 3.147

4.  A study of 57 cases of actinomycosis over a 36-year period. A diagnostic 'failure' with good prognosis after treatment.

Authors:  W C Weese; I M Smith
Journal:  Arch Intern Med       Date:  1975-12

Review 5.  Imaging of actinomycosis in various organs: a comprehensive review.

Authors:  Suk Hee Heo; Sang Soo Shin; Jin Woong Kim; Hyo Soon Lim; Hyun Ju Seon; Sook-In Jung; Yong Yeon Jeong; Heoung Keun Kang
Journal:  Radiographics       Date:  2014 Jan-Feb       Impact factor: 5.333

6.  The contribution of histopathological examination to the diagnosis of cervico-facial actinomycosis: a retrospective analysis of 68 cases.

Authors:  L Lo Muzio; G Favia; M Lacaita; A De Lillo; C Scully; A Napoli; L Lo Russo; E Maiorano
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-05-29       Impact factor: 3.267

Review 7.  Cervical actinomycosis causing spinal cord compression and multisegmental root failure: case report and review of the literature.

Authors:  H H Oruçkaptan; O Senmevsim; F Söylemezoğlu; T Ozgen
Journal:  Neurosurgery       Date:  1998-10       Impact factor: 4.654

  7 in total
  3 in total

1.  Lumbar vertebral osteomyelitis and psoas abscess caused by Actinomyces israelii after an operation under general anesthesia in a patient with end-stage renal disease: a case report.

Authors:  Yutaka Yamada; Chiharu Kinoshita; Hirokazu Nakagawa
Journal:  J Med Case Rep       Date:  2019-11-28

2.  Actinomycotic Infection of Spine - A Rare Disease with Diagnostic Challenge, an Update on Spinal Infection.

Authors:  Shailesh Hadgaonkar; Pradhyumn Rathi; Vivek Vincent; Ashok Shyam; Parag Sancheti
Journal:  J Orthop Case Rep       Date:  2021

3.  Cervicofacial Actinomycosis in the Pediatric Population: Presentation and Management.

Authors:  Karan Gandhi; Benjamin D van der Woerd; M Elise Graham; Michelle Barton; Julie E Strychowsky
Journal:  Ann Otol Rhinol Laryngol       Date:  2021-06-01       Impact factor: 1.547

  3 in total

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