| Literature DB >> 27033220 |
Laura Falcone1, Monica Casucci2.
Abstract
Secreted luciferases provide a simple, accurate, and cost-effective tool to monitor tumor response after treatment in small animal models. This protocol describes all the steps required to generate human tumor cell lines expressing this reporter gene and to monitor in vivo tumor progression after injection in immunocompromised mice by means of serial peripheral blood sampling and analysis.Entities:
Keywords: Animal models; Cancer therapy; In vivo imaging; Monitoring tumor growth in vivo; Secreted luciferases
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Year: 2016 PMID: 27033220 DOI: 10.1007/978-1-4939-3338-9_10
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745