Literature DB >> 27032753

The surgical management of necrotising enterocolitis (NEC).

Hemanshoo Sudhir Thakkar1, Kokila Lakhoo2.   

Abstract

Necrotising enterocolitis (NEC) is a neonatal surgical emergency. At its early stages, the management of NEC is largely medical using broad-spectrum antibiotics, gut rest and total parental nutrition. The only absolute indication for surgery is an intra-abdominal perforation. There are several relative indications for surgery based on clinical, biochemical and radiological parameters. Once the decision to intervene is made, several approaches may be taken. Peritoneal lavage can be used as a salvage procedure or definitive management in some cases. The most common approach taken is bowel resection with enterostomy formation. There is a role for primary anastomosis of bowel in limited NEC. In severe, multi-focal NEC a high diverting jejunostomy or "clip and drop technique" can be used. Laparoscopy has a limited role and is not widespread. The surgical complications of NEC include stoma related morbidity, anastomotic leak/stricture and short-bowel syndrome. Long-term data on neurodevelopmental outcomes is sparse but the present literature is suggestive of a negative impact in cases of surgically managed NEC. Crown
Copyright © 2016. Published by Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Anastomosis; Clip-and-drop; Enterostomy; Jejunostomy; Laparoscopy; Necrotising enterocolitis; Neurodevelopmental; Perforation; Peritoneal drain; Peritoneal lavage

Mesh:

Year:  2016        PMID: 27032753     DOI: 10.1016/j.earlhumdev.2016.03.002

Source DB:  PubMed          Journal:  Early Hum Dev        ISSN: 0378-3782            Impact factor:   2.079


  8 in total

1.  Variability in Antibiotic Regimens for Surgical Necrotizing Enterocolitis Highlights the Need for New Guidelines.

Authors:  Brian P Blackwood; Catherine J Hunter; Julia Grabowski
Journal:  Surg Infect (Larchmt)       Date:  2017-01-03       Impact factor: 2.150

2.  Neonatal independent predictors of severe NEC.

Authors:  Miriam Duci; Francesco Fascetti-Leon; Marta Erculiani; Elena Priante; Maria Elena Cavicchiolo; Giovanna Verlato; Piergiorgio Gamba
Journal:  Pediatr Surg Int       Date:  2018-04-11       Impact factor: 1.827

Review 3.  The Neurodevelopmental Perspective of Surgical Necrotizing Enterocolitis: The Role of the Gut-Brain Axis.

Authors:  Chariton Moschopoulos; Panagiotis Kratimenos; Ioannis Koutroulis; Bhairav V Shah; Anja Mowes; Vineet Bhandari
Journal:  Mediators Inflamm       Date:  2018-03-11       Impact factor: 4.711

4.  Incidence, Treatment, and Outcome Trends of Necrotizing Enterocolitis in Preterm Infants: A Multicenter Cohort Study.

Authors:  Carlos Zozaya; Inés García González; Alejandro Avila-Alvarez; Niki Oikonomopoulou; Tomás Sánchez Tamayo; Enrique Salguero; Miguel Saenz de Pipaón; Fermín García-Muñoz Rodrigo; María L Couce
Journal:  Front Pediatr       Date:  2020-05-13       Impact factor: 3.418

5.  Hematological predictors of mortality in neonates with fulminant necrotizing enterocolitis.

Authors:  Parvesh Mohan Garg; Anna O'Connor; Md Abu Yusuf Ansari; Binh Vu; Haley Hobart; Jaslyn L Paschal; Harleen Multani; Cassandra D Josephson; Victoria Okhomina
Journal:  J Perinatol       Date:  2021-03-26       Impact factor: 2.521

6.  Surgical Versus Medical Management of Necrotizing Enterocolitis With and Without Intestinal Perforation: A Retrospective Chart Review.

Authors:  Muhammad Khalid Syed; Ahmad A Al Faqeeh; Noman Saeed; Talal Almas; Tarek Khedro; Muhammad Ali Niaz; M Ali Kanawati; Salman Hussain; Hussain Mohammad; Lamees Alshaikh; Lina Alshaikh; Abdulaziz Abdulhadi; Abdulaziz Alshamlan; Saifullah Syed; Hamdy Katar Hanafi Mohamed
Journal:  Cureus       Date:  2021-06-17

Review 7.  Portal gas in neonates; is it always surgical? A case report.

Authors:  Tariq Ibrahim Altokhais
Journal:  World J Clin Cases       Date:  2020-09-06       Impact factor: 1.337

8.  Turkish Neonatal Society Necrotizing Enterocolitis Diagnosis, Treatment and Prevention Guidelines.

Authors:  Ebru Ergenekon; Cüneyt Tayman; Hilal Özkan
Journal:  Turk Arch Pediatr       Date:  2021-09
  8 in total

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