Literature DB >> 2703240

Cytogenetic analysis of in vitro fertilization (IVF) failures.

M H Pieters1, J P Geraedts, J C Dumoulin, J L Evers, M Bras, F H Kornips, P P Menheere.   

Abstract

Cytogenetic studies were carried out on 150 oocytes obtained in a human in vitro fertilization (IVF) program. Although all cells lacked signs of fertilization at light microscopy, 46 (30.7%) appeared to show cytological evidence of fertilization. At least one-third of these cells (with development arrested before first cleavage) had chromosomal aberrations. An aneuploidy rate of 35% was found in unfertilized oocytes. The results of this study explain some of the fertilization failures and of the failures of postfertilization development.

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Year:  1989        PMID： 2703240     DOI： 10.1007/BF00283693

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  17 in total

1.  Prematurely condensed human sperm chromosomes after in vitro fertilization (IVF).

Authors:  H Schmiady; K Sperling; H Kentenich; M Stauber
Journal:  Hum Genet       Date:  1986-12       Impact factor: 4.132

2.  Chromosome analysis of human oocytes failing to cleave after insemination in vitro.

Authors:  H Wramsby; K Fredga
Journal:  Hum Reprod       Date:  1987-02       Impact factor: 6.918

3.  The chromosome complement of first-cleavage mouse embryos after in vitro fertilization.

Authors:  J Santaló; A M Estop; J Egozcue
Journal:  J In Vitro Fert Embryo Transf       Date:  1986-04

4.  An improved, efficient method for analyzing human sperm chromosomes using zona-free hamster ova.

Authors:  Y Kamiguchi; K Mikamo
Journal:  Am J Hum Genet       Date:  1986-05       Impact factor: 11.025

5.  Chromosome studies of early human embryos: proof of fertilization in uncleaved human oocytes.

Authors:  L Mettler; H W Michelmann
Journal:  Ann N Y Acad Sci       Date:  1985       Impact factor: 5.691

6.  From oocyte to embryo: a model, deduced from in vitro fertilization, for natural selection against chromosome abnormalities.

Authors:  M Plachot; J de Grouchy; A M Junca; J Mandelbaum; C Turleau; P Couillin; J Cohen; J Salat-Baroux
Journal:  Ann Genet       Date:  1987

7.  Abnormal chromosome behavior in human oocytes which remained unfertilized during human in vitro fertilization.

Authors:  H Spielmann; C Krüger; M Stauber; R Vogel
Journal:  J In Vitro Fert Embryo Transf       Date:  1985-09

8.  Length of human prematurely condensed chromosomes during G0 and G1 phase.

Authors:  H Schmiady; K Sperling
Journal:  Exp Cell Res       Date:  1981-08       Impact factor: 3.905

9.  A gradual fixation method for chromosomal preparations of human oocytes.

Authors:  H Wramsby; P Liedholm
Journal:  Fertil Steril       Date:  1984-05       Impact factor: 7.329

10.  Parental origin of chromosome abnormalities in spontaneous abortions.

Authors:  G H Meulenbroek; J P Geraedts
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132
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  13 in total

1.  Frequency and patterns of premature sperm chromosome condensation in oocytes failing to fertilize after intracytoplasmic sperm injection.

Authors:  B E Rosenbusch
Journal:  J Assist Reprod Genet       Date:  2000-05       Impact factor: 3.412

Review 2.  Is there any evidence for immunologically mediated or immunologically modifiable early pregnancy failure?

Authors:  David A Clark
Journal:  J Assist Reprod Genet       Date:  2003-02       Impact factor: 3.412

3.  Triploidy after in vitro fertilization: cytogenetic analysis of human zygotes and embryos.

Authors:  M H Pieters; J C Dumoulin; R C Ignoul-Vanvuchelen; M Bras; J L Evers; J P Geraedts
Journal:  J Assist Reprod Genet       Date:  1992-02       Impact factor: 3.412

4.  Factors associated with premature chromosome condensation (PCC) following in vitro fertilization.

Authors:  M I Tejada; M R Mendoza; B Corcóstegui; J A Benito
Journal:  J Assist Reprod Genet       Date:  1992-02       Impact factor: 3.412

5.  Chromosomal analysis of unfertilized oocytes and morphologically abnormal preimplantation embryos from an in vitro fertilization program.

Authors:  G Michaeli; M Fejgin; Y Ghetler; I Ben Nun; Y Beyth; A Amiel
Journal:  J In Vitro Fert Embryo Transf       Date:  1990-12

6.  Frequency and distribution of aneuploidy in human female gametes.

Authors:  F Pellestor
Journal:  Hum Genet       Date:  1991-01       Impact factor: 4.132

7.  Assessing the chromosome copy number in metaphase II oocytes by sequential fluorescence in situ hybridization.

Authors:  M Vollmer; F Wenzel; C DeGeyter; H Zhang; W Holzgreve; P Miny
Journal:  J Assist Reprod Genet       Date:  2000-11       Impact factor: 3.412

8.  Chromosomal analysis of unfertilized human oocytes prepared by a gradual fixation-air drying method.

Authors:  Y Kamiguchi; B Rosenbusch; K Sterzik; K Mikamo
Journal:  Hum Genet       Date:  1993-01       Impact factor: 4.132

9.  Parthenogenetic activation of human oocytes by puromycin.

Authors:  P De Sutter; D Dozortsev; J Cieslak; G Wolf; Y Verlinsky; A Dyban
Journal:  J Assist Reprod Genet       Date:  1992-08       Impact factor: 3.412

10.  In vitro DNA fluorescence after in vitro fertilization (IVF) failure.

Authors:  B Van Wissen; C Eisenberg; P Debey; G Pennehouat; J Auger; O Bomsel-Helmreich
Journal:  J Assist Reprod Genet       Date:  1992-12       Impact factor: 3.412
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