Literature DB >> 27031245

Correction: Host Factors and Biomarkers Associated with Poor Outcomes in Adults with Invasive Pneumococcal Disease.

Shigeo Hanada, Satoshi Iwata, Kazuma Kishi, Miyuki Morozumi, Naoko Chiba, Takeaki Wajima, Misako Takata, Kimiko Ubukata.   

Abstract

Entities:  

Year:  2016        PMID: 27031245      PMCID: PMC4816381          DOI: 10.1371/journal.pone.0153109

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


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There is an error in the Table 3. Within the column labeled “OR (95% CI)”, the values are incorrect for the row labeled “Non-vaccine serotypes”. The correct values are: 1.5 (0.8–3.0). Please see the corrected Table 3 here.
Table 3

Risk factors associated with mortality within 28 days among patients with invasive pneumococcal disease by multivariate logistic regression analysis.

CharacteristicSurvived (n = 384)Died (n = 122)Multivariate analysis ep value f
n (%)n (%)OR (95% CI)
Age groups
    <50 y45 (11.7)5 (4.1)1-
    50–64 y87 (22.7)18 (14.8)1.6 (0.5–5.6)NS
    65–79 y155 (40.4)51 (41.8)3.0 (0.9–9.6)NS
    ≥80 y97 (25.3)48 (39.3)6.5 (2.0–21.6).002
Underlying disease
    Liver diseasea33 (8.6)17 (13.9)3.5 (1.6–7.8).002
    Lung diseaseb34 (8.9)4 (3.3)0.4 (0.1–1.4)NS
Mechanical ventilation52 (13.5)40 (32.8)3.0 (1.7–5.6)< .001
Laboratory findings c
    WBC (<4.0×103 cells/μL)39 (10.2)41 (33.6)6.9 (3.7–12.8)< .001
    Cr (≥2.0 mg/dL)46 (12.1)44 (36.4)4.5 (2.5–8.1)< .001
    LDH (≥300 IU/L)118 (32.1)61 (53.0)2.4 (1.4–4.0).001
Serotype d
    PCV7 serotypes139 (36.2)44 (36.1)1-
    PCV13 and PPSV23 serotypes182 (47.4)50 (41.0)0.8 (0.5–1.5)NS
    Non-vaccine serotypes60 (15.6)20 (23.0)1.5 (0.8–3.0)NS

a Includes chronic hepatitis or cirrhosis that was secondary to alcohol abuse or viral infection.

b Includes chronic obstructive pulmonary disease, bronchial asthma, interstitial lung disease, and bronchiectasis.

c Laboratory findings; WBC, white blood cell count; Cr, creatinine; LDH, lactate dehydrogenase.

d Serotype; PCV7, 7-valent pneumococcal conjugate vaccine; PCV13, 13-valent pneumococcal conjugate vaccine; PPSV23, 23-valent pneumococcal polysaccharide vaccine.

e Multivariate analysis; OR, odds ratio; CI, confidence interval.

f NS, not significant (p ≥ .05).

a Includes chronic hepatitis or cirrhosis that was secondary to alcohol abuse or viral infection. b Includes chronic obstructive pulmonary disease, bronchial asthma, interstitial lung disease, and bronchiectasis. c Laboratory findings; WBC, white blood cell count; Cr, creatinine; LDH, lactate dehydrogenase. d Serotype; PCV7, 7-valent pneumococcal conjugate vaccine; PCV13, 13-valent pneumococcal conjugate vaccine; PPSV23, 23-valent pneumococcal polysaccharide vaccine. e Multivariate analysis; OR, odds ratio; CI, confidence interval. f NS, not significant (p ≥ .05).
  1 in total

1.  Host Factors and Biomarkers Associated with Poor Outcomes in Adults with Invasive Pneumococcal Disease.

Authors:  Shigeo Hanada; Satoshi Iwata; Kazuma Kishi; Miyuki Morozumi; Naoko Chiba; Takeaki Wajima; Misako Takata; Kimiko Ubukata
Journal:  PLoS One       Date:  2016-01-27       Impact factor: 3.240

  1 in total

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