| Literature DB >> 27030824 |
Mallika Ghosh, Linda H Shapiro.
Abstract
Antigen cross presentation is important for effective immune responses to tumors and viral infections. Dendritic cells are professional antigen presenting cells and are unique in their ability to cross-present exogenous antigens on MHC class I molecules and activate antigen specific cytotoxic T cells. This protocol describes antigen cross presentation by dendritic cells (DCs) (bone marrow derived DCs and splenic DCs) in an in vitro and in an in vivo assay system using soluble ovalbumin protein.Entities:
Year: 2012 PMID: 27030824 PMCID: PMC4809020 DOI: 10.21769/bioprotoc.305
Source DB: PubMed Journal: Bio Protoc ISSN: 2331-8325