| Literature DB >> 27030588 |
Paul L A M Corstjens1, Anouk van Hooij2, Elisa M Tjon Kon Fat1, Susan J F van den Eeden2, Louis Wilson2, Annemieke Geluk3.
Abstract
Acute inflammatory reactions represent the major cause of irreversible neuropathy in leprosy. These tissue-destroying episodes have considerable overlap with acute immunological complications (flares) in several chronic (autoimmune) diseases that similarly warrant early detection. However, the lack of diagnostic tests impedes early diagnosis of these reactions. Here, we evaluated a user-friendly multiplex lateral flow assay for the simultaneous detection of IP-10 and anti-phenolic glycolipid I antibodies for longitudinally monitoring early onset and treatment of leprosy reactions.Entities:
Mesh:
Substances:
Year: 2016 PMID: 27030588 PMCID: PMC4895013 DOI: 10.1128/CVI.00033-16
Source DB: PubMed Journal: Clin Vaccine Immunol ISSN: 1556-679X