Literature DB >> 27030381

Limbic Encephalitis Associated With GAD65 Antibodies: Brief Review of the Relevant literature.

Maude-Marie Gagnon1, Martin Savard1.   

Abstract

Recently, many cases of autoimmune limbic encephalitis with positive GAD65 (glutamic acid decarboxylase) antibodies have been described in the scientific literature. However, it remains an understudied topic of great relevance to practicing neurologists. Thus, we report here a review of published cases, in English, of autoimmune limbic encephalitis with this type of antibodies, focusing on presenting symptoms and signs, associated conditions, and findings upon investigation. We also report treatment responses. We aim to offer a better description of the clinical spectrum of autoimmune limbic encephalitis associated with GAD65 antibodies as well as to expose its paraclinical features and outcome.

Entities:  

Keywords:  CNS inflammation; cognitive impairment; immune system; neuroimmunology; neuroinflammation; neurology – clinical; seizures; status epilepticus

Mesh:

Substances:

Year:  2016        PMID: 27030381     DOI: 10.1017/cjn.2016.13

Source DB:  PubMed          Journal:  Can J Neurol Sci        ISSN: 0317-1671            Impact factor:   2.104


  9 in total

Review 1.  Treating Immune-Related Epilepsy.

Authors:  Sonal Bhatia; Sarah E Schmitt
Journal:  Curr Neurol Neurosci Rep       Date:  2018-02-14       Impact factor: 5.081

2.  Recurrent seizures of autoimmune origin: emerging phenotypes.

Authors:  Mathilde Goudot; Solène Frismand; Lucie Hopes; Antoine Verger; Bastien Joubert; Jérôme Honnorat; Louise Tyvaert
Journal:  J Neurol       Date:  2021-02-27       Impact factor: 4.849

3.  Case Report: Autoimmune Encephalitis Associated With Anti-glutamic Acid Decarboxylase Antibodies: A Pediatric Case Series.

Authors:  Changhong Ren; Haitao Ren; Xiaotun Ren; Weihua Zhang; Jiuwei Li; Lifang Dai; Hongzhi Guan; Fang Fang
Journal:  Front Neurol       Date:  2021-04-12       Impact factor: 4.003

Review 4.  Neuropsychiatric Disorders Due to Limbic Encephalitis: Immunologic Aspect.

Authors:  Yu-Chia Kao; Ming-I Lin; Wen-Chin Weng; Wang-Tso Lee
Journal:  Int J Mol Sci       Date:  2020-12-31       Impact factor: 5.923

5.  Psychotic Symptoms as the Initial Presentation of a Long-Lasting Misdiagnosed Anti-GAD65 Autoimmune Encephalitis: An Emblematic Case and Literature Review.

Authors:  Jianjun Wang; Shenglan Gong; Fanxin Kong; Dongbin Cai; Binqing Huang; Haotao Zheng; Songjun Lin; Jinfang Li; Tianfeng Zhang
Journal:  Front Psychiatry       Date:  2022-02-23       Impact factor: 4.157

6.  Case Report: Multisystem Autoimmune and Overlapping GAD65-Antibody-Associated Neurological Disorders With Beneficial Effect of Epilepsy Surgery and Rituximab Treatment.

Authors:  Petia Dimova; Krassimir Minkin
Journal:  Front Neurol       Date:  2022-01-20       Impact factor: 4.003

7.  Autoimmune encephalitis: the first observational study from Iran.

Authors:  Masoud Etemadifar; Ali Aghababaei; Hosein Nouri; Parisa K Kargaran; Shaghayegh Mohammadi; Mehri Salari
Journal:  Neurol Sci       Date:  2021-07-30       Impact factor: 3.830

8.  Intravenous methylprednisolone or immunoglobulin for anti-glutamic acid decarboxylase 65 antibody autoimmune encephalitis: which is better?

Authors:  Tao-Ran Li; Yu-Di Zhang; Qun Wang; Xiao-Qiu Shao; Zhi-Mei Li; Rui-Juan Lv
Journal:  BMC Neurosci       Date:  2020-03-30       Impact factor: 3.288

Review 9.  Paraneoplastic Diseases of the Central Nervous System.

Authors:  Jonathan Galli; John Greenlee
Journal:  F1000Res       Date:  2020-03-06
  9 in total

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