Literature DB >> 27028

[Analytical data of flunitrazepam (rohypnol), a new benzodiazepine-derivative, in special consideration of its metabolites (author's transl)].

S Ebel, H Schütz.   

Abstract

The article describes analytical data (TLC, GLC, IR, UV and MS) of flunitrazepam, 7-amino-flunitrazepam, desmethylflunitrazepam, 3-hydroxyflunitrazepam, 7-amino-desmethyl-flunitrazepam and many other benzodiazepine-derivatives, especially aminobenzophenones. Also extraction from biological specimen is reported.

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Year:  1978        PMID： 27028     DOI： 10.1007/BF00203870

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN： 0044-3433


  13 in total

1.  Determination of 1,4-benzodiazepines and -diazepin-2-ones in blood by electron-capture gas-liquid chromatography.

Authors:  J A de Silva; I Bekersky; C V Puglisi; M A Brooks; R E Weinfeld
Journal:  Anal Chem       Date:  1976-01       Impact factor: 6.986

2.  [The use of combined spectroscopy in analytical toxicology (author's transl)].

Authors:  J Bäumler; H Brandenberger
Journal:  Z Rechtsmed       Date:  1975-11-28

3.  [Gas chromatographic contribution to the analysis of pyridinechromophore and phenylchromophore bases].

Authors:  D Post
Journal:  Beitr Gerichtl Med       Date:  1976

4.  Determination of clonazepam and flunitrazepam in blood and urine by electron-capture GLC.

Authors:  J A De Silva; C V Puglisi; N Munno
Journal:  J Pharm Sci       Date:  1974-04       Impact factor: 3.534

5.  Pharmacokinetic profiles of clonazepam in dog and humans and of flunitrazepam in dog.

Authors:  S A Kaplan; K Alexander; M L Jack; C V Puglisi; J A De Silva; T L Lee; R E Weinfeld
Journal:  J Pharm Sci       Date:  1974-04       Impact factor: 3.534

6.  Plasma levels and derived pharmacokinetic characteristics of unchanged nitrazepam in man.

Authors:  J Rieder
Journal:  Arzneimittelforschung       Date:  1973-02

7.  [Synthesis and analysis of possible nitrazepam-metabolites. 4. Chemistry and analysis of benzodiazepin-derivatives].

Authors:  K H Beyer; W Sadée
Journal:  Arch Pharm Ber Dtsch Pharm Ges       Date:  1969-02

8.  [Retention indices for gas chromatographic identification of drugs (authors transl)].

Authors:  H Berninger; M R Möller
Journal:  Arch Toxicol       Date:  1977-08-09       Impact factor: 5.153

9.  Determination of clonazepam and flunitrazepam in blood by electron-capture gas-liquid chromatography.

Authors:  J A de Silva; I Bekersky
Journal:  J Chromatogr       Date:  1974-11-06

10.  [Studies on the detection of clonazepam and its main metabolites considering in particular thin-layer chromatography discrimination of nitrazepam and its major metabolic products (author's transl)].

Authors:  S Ebel; H Schütz
Journal:  Arzneimittelforschung       Date:  1977-02
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  1 in total

1.  [GLC-data of 19 hydrolysis-derivatives rised from 12 important benzodiazepines and 17 main-metabolites (author's transl)].

Authors:  H Schütz; V Westenberger
Journal:  Z Rechtsmed       Date:  1978-09-28
  1 in total

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