Literature DB >> 2702727

The prevention of nitrosomethylurea-induced mammary tumors by d-limonene and orange oil.

T H Maltzman1, L M Hurt, C E Elson, M A Tanner, M N Gould.   

Abstract

The monocyclic monoterpenoid d-limonene and its source, orange oil, were found to prevent rat mammary carcinomas induced by the direct-acting carcinogen nitrosomethylurea. This chemopreventive effect was limited to the promotion/progression stage in this carcinogenesis model.

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Year:  1989        PMID： 2702727     DOI： 10.1093/carcin/10.4.781

Source DB:  PubMed          Journal:  Carcinogenesis        ISSN： 0143-3334            Impact factor:   4.944


  22 in total

Review 1.  Farnesyl protein transferase inhibitors and other therapies targeting the Ras signal transduction pathway.

Authors:  D W End
Journal:  Invest New Drugs       Date:  1999       Impact factor: 3.850

Review 2.  Targeting apoptosis pathway with natural terpenoids: implications for treatment of breast and prostate cancer.

Authors:  Huanjie Yang; Q Ping Dou
Journal:  Curr Drug Targets       Date:  2010-06       Impact factor: 3.465

3.  Tumorigenesis of rat mammary epithelial cells by N-nitroso-N-methylurea in an in vitro system: characterization of the microtumors.

Authors:  J R Laduca; D K Sinha
Journal:  In Vitro Cell Dev Biol Anim       Date:  1996-04       Impact factor: 2.416

Review 4.  Dietary factors modifying breast cancer risk and relation to time of intake.

Authors:  Airo Tsubura; Norihisa Uehara; Yasuhiko Kiyozuka; Nobuaki Shikata
Journal:  J Mammary Gland Biol Neoplasia       Date:  2005-01       Impact factor: 2.673

5.  Plasma metabolomic profiles of breast cancer patients after short-term limonene intervention.

Authors:  Jessica A Miller; Kirk Pappan; Patricia A Thompson; Elizabeth J Want; Alexandros P Siskos; Hector C Keun; Jacob Wulff; Chengcheng Hu; Julie E Lang; H-H Sherry Chow
Journal:  Cancer Prev Res (Phila)       Date:  2014-11-11

Review 6.  Mammary tumorigenesis and chemoprevention studies in carcinogen-treated rats.

Authors:  C Ip
Journal:  J Mammary Gland Biol Neoplasia       Date:  1996-01       Impact factor: 2.673

7.  Safety and Feasibility of Topical Application of Limonene as a Massage Oil to the Breast.

Authors:  Jessica A Miller; Patricia A Thompson; Iman A Hakim; Ana Maria Lopez; Cynthia A Thomson; Wade Chew; Chiu-Hsieh Hsu; H-H Sherry Chow
Journal:  J Cancer Ther       Date:  2012-10

8.  Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene.

Authors:  J D Haag; M N Gould
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

9.  Identification of metabolites of the antitumor agent d-limonene capable of inhibiting protein isoprenylation and cell growth.

Authors:  P L Crowell; S Lin; E Vedejs; M N Gould
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

10.  Human breast tissue disposition and bioactivity of limonene in women with early-stage breast cancer.

Authors:  Jessica A Miller; Julie E Lang; Michele Ley; Ray Nagle; Chiu-Hsieh Hsu; Patricia A Thompson; Catherine Cordova; Amy Waer; H-H Sherry Chow
Journal:  Cancer Prev Res (Phila)       Date:  2013-04-03
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