| Literature DB >> 27025491 |
P D Kim1,2, S S Zamay1,3,4, T N Zamay5,6, V S Prokopenko7, O S Kolovskaya1,3, G S Zamay1,3, V Ya Princ2, V A Seleznev2, A I Komonov2, E A Spivak1, R Yu Rudenko8,4, A V Dubinina1,3,8, A V Komarov1,8, V V Denisenko1,8, M A Komarova1,3, A E Sokolov1,4, A A Narodov1,3, V P Zjivaev7, A S Zamay1,3,9.
Abstract
Here we describe a method of forming large arrays (up to 10(9) pieces) of free magnetic Ni-nanodisks 50 nm thick coated on both sides with layers of 5 nm thick Au. The antitumor effect of the magnetic nickel gold-coated nanodisks and DNA aptamer conjugates was evaluated in vivo and in vitro. Under the influence of rotating magnetic field, the studied nanodisks can cause the death of Ehrlich ascites carcinoma cells.Entities:
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Year: 2016 PMID： 27025491 DOI： 10.1134/S1607672916010154
Source DB: PubMed Journal: Dokl Biochem Biophys ISSN： 1607-6729 Impact factor: 0.788