Literature DB >> 27025483

Audiogenic epilepsy and GABAergic system of the colliculus inferior in Krushinsky-Molodkina rats.

G M Solius1, A V Revishchin2, G V Pavlova3, I I Poletaeva1.   

Abstract

GABAergic brain system is an important link in the pathological circuits of rodent audiogenic epilepsy (AE). The number of GABAergic neurons in the inferior colliculi of KM strain rats (AE prone) was not different from that of the control non-prone strain. At the same time, the glutamate decarboxylase mRNA expression (the key enzyme of GABA synthesis) was 5 times higher than in control. The data evidence that the GABAergic system does play an important role in AE proneness.

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Year:  2016        PMID： 27025483     DOI： 10.1134/S1607672916010099

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  9 in total

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2.  A new population of calretinin-positive cells, presumptively neurons, with polymorphous spines in the mouse forebrain.

Authors:  A V Revishchin; V E Okhotin; L I Korochkin; G V Pavlova
Journal:  Neurosci Behav Physiol       Date:  2010-05-14

Review 3.  [Rats of Krushinsky-Molodkina strain: studies of audiogenic epilepsy, vascular pathology, and behavior].

Authors:  A F Semiokhina; I B Fedotova; I I Poletaeva
Journal:  Zh Vyssh Nerv Deiat Im I P Pavlova       Date:  2006 May-Jun       Impact factor: 0.437

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Authors:  C L Faingold; G Gehlbach; D M Caspary
Journal:  Exp Neurol       Date:  1986-07       Impact factor: 5.330

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Journal:  Brain Res       Date:  1985-12-30       Impact factor: 3.252

6.  The inferior colliculus of GEPRs contains greater numbers of cells that express glutamate decarboxylase (GAD67) mRNA.

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Journal:  Epilepsy Res       Date:  1993-02       Impact factor: 3.045

7.  Blockade of GABA uptake with tiagabine inhibits audiogenic seizures and reduces neuronal firing in the inferior colliculus of the genetically epilepsy-prone rat.

Authors:  C L Faingold; M E Randall; C A Anderson
Journal:  Exp Neurol       Date:  1994-04       Impact factor: 5.330

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Journal:  J Hirnforsch       Date:  1994

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Authors:  I B Fedotova; Z A Kostyna; N M Surina; I I Poletaeva
Journal:  Genetika       Date:  2012-06
  9 in total
  2 in total

1.  Audiogenic Epilepsy and Structural Features of Superior Colliculus in KM Rats.

Authors:  A V Revishchin; G M Solus; I I Poletaeva; G V Pavlova
Journal:  Dokl Biochem Biophys       Date:  2018-03-14       Impact factor: 0.788

Review 2.  Cannabinoids in Audiogenic Seizures: From Neuronal Networks to Future Perspectives for Epilepsy Treatment.

Authors:  Willian Lazarini-Lopes; Raquel A Do Val-da Silva; Rui M P da Silva-Júnior; Alexandra O S Cunha; Norberto Garcia-Cairasco
Journal:  Front Behav Neurosci       Date:  2021-02-11       Impact factor: 3.558
  2 in total

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