| Literature DB >> 27025478 |
D G Sochivko1, A A Fedorov2, D A Varlamov3, V E Kurochkin4, R V Petrov5.
Abstract
The paper reviews different approaches to the mathematical analysis of polymerase chain reaction (PCR) kinetic curves. The basic principles of PCR mathematical analysis are presented. Approximation of PCR kinetic curves and PCR efficiency curves by various functions is described. Several PCR models based on chemical kinetics equations are suggested. Decision criteria for an optimal function to describe PCR efficiency are proposed.Mesh:
Year: 2016 PMID: 27025478 DOI: 10.1134/S160767291601004X
Source DB: PubMed Journal: Dokl Biochem Biophys ISSN: 1607-6729 Impact factor: 0.788