Literature DB >> 27021104

Effect of Repeated 1-h Episodes of Immobilization Stress on Activity of Glucocorticoid Metabolism Enzymes in the Liver.

V E Tseilikman1, D A Kozochkin2, A I Sinitskii2, O B Tseylikman3, M S Lapshin3, O V Kuzina2, M V Komel'kova2, I B Telesheva2.   

Abstract

Differences in corticosterone level associated with different activity of glucocorticoid-oxidizing enzymes in the liver were revealed in rats exposed to stress. Pro-inflammatory changes in the liver were associated with enhanced CYP3A-dependent monooxygenation.

Entities:  

Keywords:  11β-hydroxysteroid dehydrogenase-2, CYP3A; corticosterone; stress

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Year:  2016        PMID： 27021104     DOI： 10.1007/s10517-016-3230-8

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  1 in total

1.  The Link between Activities of Hepatic 11beta-Hydroxysteroid Dehydrogenase-1 and Monoamine Oxidase-A in the Brain Following Repeated Predator Stress: Focus on Heightened Anxiety.

Authors:  Vadim Tseilikman; Maxim Lapshin; Igor Klebanov; George Chrousos; Maria Vasilieva; Anton Pashkov; Julia Fedotova; David Tseilikman; Vladislav Shatilov; Eugenia Manukhina; Olga Tseilikman; Alexey Sarapultsev; H Fred Downey
Journal:  Int J Mol Sci       Date:  2022-04-28       Impact factor: 6.208
  1 in total

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