| Literature DB >> 27021066 |
João Inácio Da Silva Filho1, Célio Vander Nunes2, Dorotéa Vilanova Garcia2,3, Mauricio Conceição Mario2, Fábio Giordano2, Jair Minoro Abe2, Marcos Tadeu Tavares Pacheco2,3, Landulfo Silveira2,3.
Abstract
Paraconsistent logic (PL) is a type of non-classical logic that accepts contradiction as a fundamental concept and has produced valuable results in the analysis of uncertainties. In this work, algorithms based on a type of PL-paraconsistent annotated logic of two values (PAL2v)-are interconnected into a network of paraconsistent analysis (PANnet). PANnet was applied to a dataset comprising 146 Raman spectra of skin tissue biopsy fragments of which 30 spectra were determined to represent normal skin tissue (N), 96 were determined to represent tissue with basal cell carcinoma, and 19 were determined to be tissue with melanoma (MEL). In this database, paraconsistent analysis was able to correctly discriminate 136 out of a total of 145 fragments, obtaining a 93.793 % correct diagnostic accuracy. The application of PAL2v in the analysis of Raman spectroscopy signals produces better discrimination of cells than conventional statistical processes and presents a good graphical overview through its associated lattice structure. The technique of PAL2v-based data processing can be fundamental in the development of a computational tool dedicated to support the diagnosis of skin cancer using Raman spectroscopy.Entities:
Keywords: Algorithm; Paraconsistent annotated logic; Skin cancer; Spectroscopy; Uncertainties
Mesh:
Year: 2016 PMID: 27021066 DOI: 10.1007/s11517-016-1471-3
Source DB: PubMed Journal: Med Biol Eng Comput ISSN: 0140-0118 Impact factor: 2.602