Literature DB >> 27020772

Botulinum toxin as a therapeutic agent to prevent relapse in deep bite patients.

Thomas Mücke1, Anja Löffel2, Anastasios Kanatas3, Sandy Karnezi3, Majeed Rana4, Andreas Fichter2, Stephan Haarmann2, Klaus-Dietrich Wolff2, Denys John Loeffelbein2.   

Abstract

INTRODUCTION: The etiology of deep bite is multifactorial. One of the causes is increased muscular activity. This makes the treatment of deep bite malocclusions difficult and often results in relapse in many cases. In this work we compared patients with surgical orthognathic treatment only and surgical orthognathic treatment with additional injections of botulinum toxin after mandibular advancement for class II division 2 malocclusion.
MATERIAL AND METHODS: This is a prospective study. Adult patients were assessed pretreatment (T1), posttreatment (T2), and long-term after 1 year (T3). In total, 32 patients (mean age, 30.7 years; 23 women and 9 men) reached the study end point (T3); 24 patients were treated without botulinum toxin and 8 patients received preoperative injections of botulinum toxin.
RESULTS: Significant differences between both groups were observed, with a more stable result for the experimental group treated with botulinum toxin. DISCUSSION: In a selective group of adult patients with a class II division II incisor relationship and with a class II skeletal base, botulinum toxin injections can effectively prevent relapse. This may present an alternative to a conventional myotomy.
Copyright © 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Botulinum toxin; Cephalometry; Class II division 2 malocclusion; Deep bite; Muscular paralysis; Relapse; Stability

Mesh:

Substances:

Year:  2016        PMID: 27020772     DOI: 10.1016/j.jcms.2016.01.021

Source DB:  PubMed          Journal:  J Craniomaxillofac Surg        ISSN: 1010-5182            Impact factor:   2.078


  4 in total

1.  Ultrasound dimensional changes of the anterior belly of the digastric muscle induced by orthognathic surgery and botulinum toxin A injection in Class II malocclusion.

Authors:  Alina Coclici; Raluca Ancuta Roman; Simion Bran; Emil Crasnean; Mihaela Baciut; Cristian Dinu; Mihaela Hedesiu
Journal:  Oral Radiol       Date:  2021-01-09       Impact factor: 1.852

2.  Use of non-surgical aesthetic refinement after orthognathic surgery: Case studies.

Authors:  Ricardo Grillo; Alexandre M Borba; Ana Paula C B Lima; Marcos C Pitta; Regiane Veronesi; Claudio R P Jodas
Journal:  J Taibah Univ Med Sci       Date:  2021-09-04

Review 3.  Correction of Malocclusion by Botulinum Neurotoxin Injection into Masticatory Muscles.

Authors:  Hyun Seok; Seong-Gon Kim
Journal:  Toxins (Basel)       Date:  2018-01-02       Impact factor: 4.546

Review 4.  The role of muscular traction in the occurrence of skeletal relapse after advancement bilateral sagittal split osteotomy (BSSO): A systematic review.

Authors:  Maxim Van den Bempt; Shankeeth Vinayahalingam; Michael D Han; Stefaan J Bergé; Tong Xi
Journal:  Orthod Craniofac Res       Date:  2021-06-23       Impact factor: 2.563

  4 in total

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