Literature DB >> 270207

Basophilic differentiation of chronic myelogenous leukaemia cells in vitro.

I Miyoshi, H Uchida, T Tsubota, I Kubonish, S Hiraki, K Kitajima.   

Abstract

Peripheral leucocytes from 10 patients with chronic myelogenous leukaemia (CML) were cultured in liquid medium and observed morphologically for 6 to 10 weeks. All cultures showed in increased proportion of mature basophilis at about 3 weeks and most cultures consisted predominantly of mature basophilis at about 5 weeks. The results indicate preferential basophilic differentiation of CML leucocytes in vitro and are consistent with basophilia frequently observed in CML patients.

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Year:  1977        PMID: 270207     DOI: 10.1111/j.1600-0609.1977.tb01481.x

Source DB:  PubMed          Journal:  Scand J Haematol        ISSN: 0036-553X


  6 in total

Review 1.  Basophils in human disease.

Authors:  E B Mitchell; P W Askenase
Journal:  Clin Rev Allergy       Date:  1983-09

2.  Growth of human basophil lines derived from chronic myelocytic leukaemia cells in vitro: ultrastructure and X-ray microanalysis studies.

Authors:  P Fishman; M Djaldetti; J Hart; B Sredni
Journal:  Immunology       Date:  1985-05       Impact factor: 7.397

3.  Basophil production.

Authors:  J A Denburg; M Davison; J Bienenstock
Journal:  J Clin Invest       Date:  1980-02       Impact factor: 14.808

4.  Ultrastructure of blastic crisis in osteomyelofibrosis. A report of 2 cases with some unusual features.

Authors:  J Thiele; K F Vykoupil; A Georgii
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1980

5.  Factor-dependent in vitro growth of human normal bone marrow-derived basophil-like cells.

Authors:  K Tadokoro; B M Stadler; A L De Weck
Journal:  J Exp Med       Date:  1983-09-01       Impact factor: 14.307

6.  Direct transplantation of chronic myelogenous leukemia cells into nude mice and establishment of a leukemic stem cell (Ph1+, CD34+) line dependent on mouse bone marrow stromal cells in vitro.

Authors:  I Kubonishi; S Takeuchi; Y Uemura; M Kamioka; Y Asahi; Y Ohtsuki; I Miyoshi
Journal:  Jpn J Cancer Res       Date:  1995-05
  6 in total

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