Literature DB >> 27020561

Multiple sclerosis: Fingolimod failure in progressive MS INFORMS future trials.

Andrew L Smith1, Jeffrey A Cohen1.   

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Year:  2016        PMID: 27020561     DOI: 10.1038/nrneurol.2016.37

Source DB:  PubMed          Journal:  Nat Rev Neurol        ISSN: 1759-4758            Impact factor:   42.937


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  9 in total

1.  Oral fingolimod (FTY720) for relapsing multiple sclerosis.

Authors:  Ludwig Kappos; Jack Antel; Giancarlo Comi; Xavier Montalban; Paul O'Connor; Chris H Polman; Tomas Haas; Alexander A Korn; Goeril Karlsson; Ernst W Radue
Journal:  N Engl J Med       Date:  2006-09-14       Impact factor: 91.245

2.  Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): a double-blind, randomised, placebo-controlled, phase 3 trial.

Authors:  Peter A Calabresi; Ernst-Wilhelm Radue; Douglas Goodin; Douglas Jeffery; Kottil W Rammohan; Anthony T Reder; Timothy Vollmer; Mark A Agius; Ludwig Kappos; Tracy Stites; Bingbing Li; Linda Cappiello; Philipp von Rosenstiel; Fred D Lublin
Journal:  Lancet Neurol       Date:  2014-03-28       Impact factor: 44.182

3.  Glatiramer acetate in primary progressive multiple sclerosis: results of a multinational, multicenter, double-blind, placebo-controlled trial.

Authors:  Jerry S Wolinsky; Ponnada A Narayana; Paul O'Connor; Patricia K Coyle; Corey Ford; Kenneth Johnson; Aaron Miller; Lillian Pardo; Shaul Kadosh; David Ladkani
Journal:  Ann Neurol       Date:  2007-01       Impact factor: 10.422

Review 4.  Clinical trials in progressive multiple sclerosis: lessons learned and future perspectives.

Authors:  Daniel Ontaneda; Robert J Fox; Jeremy Chataway
Journal:  Lancet Neurol       Date:  2015-02       Impact factor: 44.182

Review 5.  Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis.

Authors:  Jeffrey A Cohen; Jerold Chun
Journal:  Ann Neurol       Date:  2011-05       Impact factor: 10.422

6.  Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis.

Authors:  Jeffrey A Cohen; Frederik Barkhof; Giancarlo Comi; Hans-Peter Hartung; Bhupendra O Khatri; Xavier Montalban; Jean Pelletier; Ruggero Capra; Paolo Gallo; Guillermo Izquierdo; Klaus Tiel-Wilck; Ana de Vera; James Jin; Tracy Stites; Stacy Wu; Shreeram Aradhye; Ludwig Kappos
Journal:  N Engl J Med       Date:  2010-01-20       Impact factor: 91.245

7.  Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial.

Authors:  Kathleen Hawker; Paul O'Connor; Mark S Freedman; Peter A Calabresi; Jack Antel; Jack Simon; Stephen Hauser; Emmanuelle Waubant; Timothy Vollmer; Hillel Panitch; Jiameng Zhang; Peter Chin; Craig H Smith
Journal:  Ann Neurol       Date:  2009-10       Impact factor: 10.422

8.  Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial.

Authors:  Fred Lublin; David H Miller; Mark S Freedman; Bruce A C Cree; Jerry S Wolinsky; Howard Weiner; Catherine Lubetzki; Hans-Peter Hartung; Xavier Montalban; Bernard M J Uitdehaag; Martin Merschhemke; Bingbing Li; Norman Putzki; Fonda C Liu; Dieter A Häring; Ludwig Kappos
Journal:  Lancet       Date:  2016-01-28       Impact factor: 79.321

Review 9.  Pathological mechanisms in progressive multiple sclerosis.

Authors:  Don H Mahad; Bruce D Trapp; Hans Lassmann
Journal:  Lancet Neurol       Date:  2015-02       Impact factor: 44.182

  9 in total
  3 in total

Review 1.  Dynamic glial response and crosstalk in demyelination-remyelination and neurodegeneration processes.

Authors:  Tianci Chu; Lisa B E Shields; Wenxin Zeng; Yi Ping Zhang; Yuanyi Wang; Gregory N Barnes; Christopher B Shields; Jun Cai
Journal:  Neural Regen Res       Date:  2021-07       Impact factor: 5.135

2.  A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials.

Authors:  C Eleuteri; S Olla; C Veroni; R Umeton; R Mechelli; S Romano; M C Buscarinu; F Ferrari; G Calò; G Ristori; M Salvetti; C Agresti
Journal:  Sci Rep       Date:  2017-04-07       Impact factor: 4.379

Review 3.  The Role of Astrocytes in Multiple Sclerosis.

Authors:  Gerald Ponath; Calvin Park; David Pitt
Journal:  Front Immunol       Date:  2018-02-19       Impact factor: 7.561

  3 in total

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