Literature DB >> 27020388

Paediatric melanoma.

Benjamin A Wood1.   

Abstract

Cutaneous melanoma occurs only rarely in children under 10 years of age. Mimics of melanoma, including Spitz naevi and proliferative nodules in congenital melanocytic naevi are much more frequent in this age group. Melanoma arising in congenital melanocytic naevus is uncommon, but can show aggressive behaviour. Although spitzoid lesions constitute the majority of 'diagnostically challenging' cases, they are an uncommon cause of mortality in this age group. Among lesions with undoubted metastatic potential, there are biologically distinct tumours which differ significantly in behaviour from the common types of melanoma seen in adults. In patients over 10 years of age and increasingly into the late adolescent years, melanoma is a relatively common neoplasm. Just as in adult patients, care should be taken to exclude melanoma mimics. Particular care is warranted in this older age group in the assessment of lesions with spitzoid morphology as there is significant potential for both over-and under-diagnosis.
Copyright © 2015 The Royal College of Pathologists of Australasia. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Melanoma; Spitz naevus; adolescent; atypical Spitz tumour; atypical proliferative nodule; childhood; congenital melanocytic naevus; congenital melanoma; paediatric; proliferative nodule; spitzoid melanoma

Mesh:

Year:  2016        PMID: 27020388     DOI: 10.1016/j.pathol.2015.12.001

Source DB:  PubMed          Journal:  Pathology        ISSN: 0031-3025            Impact factor:   5.306


  5 in total

1.  Genomic analysis and clinical management of adolescent cutaneous melanoma.

Authors:  Roy Rabbie; Mamunur Rashid; Ana M Arance; Marcelo Sánchez; Gemma Tell-Marti; Miriam Potrony; Carles Conill; Remco van Doorn; Stefan Dentro; Nelleke A Gruis; Pippa Corrie; Vivek Iyer; Carla Daniela Robles-Espinoza; Joan A Puig-Butille; Susana Puig; David J Adams
Journal:  Pigment Cell Melanoma Res       Date:  2017-04-19       Impact factor: 4.693

2.  An 18-year Study of Malignant Melanoma in Childhood and Adolescence.

Authors:  Sarah Al-Himdani; N Naderi; I S Whitaker; N W Jones
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-08-30

3.  Management of Residual Spitz Nevus in Surgical Specimens following Biopsy and Excision.

Authors:  Usha E A Beijnen; Landis R Walsh; Laura C Nuzzi; Birgitta A R Schmidt; Brian I Labow; Amir H Taghinia
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-12-18

4.  Pediatric Melanoma and Drug Development.

Authors:  Klaus Rose; Jane M Grant-Kels
Journal:  Children (Basel)       Date:  2018-03-20

5.  Are Regulatory Age Limits in Pediatric Melanoma Justified?

Authors:  Klaus Rose; Philip D Walson
Journal:  Curr Ther Res Clin Exp       Date:  2019-01-18
  5 in total

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