Literature DB >> 27020270

Is it safe to perform adenotonsillectomy in children with Down syndrome?

Ali Cemal Yumusakhuylu1,2, Adem Binnetoglu3, Berat Demir4, Tekin Baglam4, Murat Sari4.   

Abstract

This retrospective review aims to evaluate the postoperative morbidity and mortality of 30 patients with Down syndrome who underwent adenotonsillectomy between June 2012 and December 2015 in a tertiary referral center. Mean age was 7.8 with a range of 3-12. There were 20 (66.6 %) male and ten (33.3 %) female patients. Mean follow-up was 23 months with a range of 7-43 months. 23 (76.6 %) of 30 patients had been operated due to obstructive tonsillar and adenoid hypertrophy, whereas seven (23.3 %) of them operated for chronic recurrent infections. All of the patients had undergone adenotonsillectomy operation; one patient had also bilateral tympanostomy tube insertion. Hospital stay was noted 1.3 days in average with a range of 1-3 days. Anesthetic complications of persistent bradycardia and postextubation respiratory difficulty occurred in two (6.6) patients. Patient who had intraoperative bradycardia necessitated intensive care unit stay and pacemaker implantation during follow-up. 3 (10 %) patients had late onset hemorrhage between days 7 and 10 and required intraoperative bleeding control. We did not experience any other morbidity and mortality except the abovementioned ones. In conclusion, adenotonsillectomy in patients with Down syndrome is a worthwhile operation with certain risks and these operations should better be performed by the tertiary referral centers which have the capacity to deal with the complications.

Entities:  

Keywords:  Adenoidectomy; Bradycardia; Complication; Down syndrome; Obstructive sleep apnea; Tonsillectomy

Mesh:

Year:  2016        PMID: 27020270     DOI: 10.1007/s00405-016-4012-7

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  19 in total

1.  Changes in central apnea index following pediatric adenotonsillectomy.

Authors:  Cristina M Baldassari; Jessica Kepchar; Lucas Bryant; Hind Beydoun; Sukgi Choi
Journal:  Otolaryngol Head Neck Surg       Date:  2011-11-10       Impact factor: 3.497

2.  The prevalence of airway problems in children with Down's syndrome.

Authors:  Jane Hamilton; May Maxime Corazon Yaneza; William Andrew Clement; Haytham Kubba
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2015-12-08       Impact factor: 1.675

3.  Effect of Adenotonsillectomy on Central and Obstructive Sleep Apnea in Children with Down Syndrome.

Authors:  Prasad John Thottam; Sukgi Choi; Jeffrey P Simons; Dennis J Kitsko
Journal:  Otolaryngol Head Neck Surg       Date:  2015-06-04       Impact factor: 3.497

4.  Postoperative complications after tonsillectomy and adenoidectomy in children with Down syndrome.

Authors:  N A Goldstein; D R Armfield; L A Kingsley; L M Borland; G C Allen; J C Post
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1998-02

5.  Pathogenesis of non-traumatic atlanto-axial subluxation (Grisel's syndrome).

Authors:  N R Welinder; P Hoffmann; S Håkansson
Journal:  Eur Arch Otorhinolaryngol       Date:  1997       Impact factor: 2.503

6.  Respiratory patterns during sleep in Down's syndrome:importance of central apnoeas.

Authors:  R Ferri; L Curzi-Dascalova; S Del Gracco; M Elia; S A Musumeci; M C Stefanini
Journal:  J Sleep Res       Date:  1997-06       Impact factor: 3.981

7.  Hemodynamic changes in children with Down syndrome during and following inhalation induction of anesthesia with sevoflurane.

Authors:  Wenyu Bai; Terri Voepel-Lewis; Shobha Malviya
Journal:  J Clin Anesth       Date:  2010-12       Impact factor: 9.452

8.  Cine magnetic resonance imaging: evaluation of persistent airway obstruction after tonsil and adenoidectomy in children with Down syndrome.

Authors:  Sally R Shott; Lane F Donnelly
Journal:  Laryngoscope       Date:  2004-10       Impact factor: 3.325

9.  OSAS in Down syndrome: T&A versus T&A plus lateral pharyngoplasty.

Authors:  James A Merrell; Sally R Shott
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2007-05-29       Impact factor: 1.675

10.  Upper airway obstruction in children with Down syndrome.

Authors:  I N Jacobs; R F Gray; N W Todd
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1996-09
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  2 in total

1.  Risk factors for respiratory adverse events after adenoidectomy and tonsillectomy in children with down syndrome: a retrospective cohort study.

Authors:  Lena Xiao; Nicholas Barrowman; Franco Momoli; Kimmo Murto; Matthew Bromwich; Sherri L Katz
Journal:  Eur J Pediatr       Date:  2022-03-12       Impact factor: 3.183

Review 2.  Obstructive sleep apnea in patients with Down syndrome: current perspectives.

Authors:  Ryne Simpson; Anthony A Oyekan; Zarmina Ehsan; David G Ingram
Journal:  Nat Sci Sleep       Date:  2018-09-13
  2 in total

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