Literature DB >> 27018626

Assessing the Risk of Prehospital Administration of Naloxone with Subsequent Refusal of Care.

Michael Levine, Stephen Sanko, Marc Eckstein.   

Abstract

BACKGROUND: EMS providers frequently encounter opioid-toxic patients who receive naloxone and then refuse further medical care. Older studies revealed this practice to be safe. In light of the evolving patterns of opioid abuse, this study attempted to determine the safety of this practice.
METHODS: This is a retrospective review of all patient encounters by the Los Angeles Fire Department (LAFD) between July 1, 2011-December 31, 2013. All LAFD patient encounters are stored electronically. These electronic records were reviewed for subjects who received naloxone had a documented respiratory rate (RR) less than 12, and subsequently refused transport. Data abstracted included name, social security number (SSN), date of birth (DOB), date of EMS encounter, age, and treatment rendered. The names, SSN, and DOB, as available, were supplied to the coroner's office. The Coroner's records were reviewed to determine if a patient with the same or similar name (e.g., Jon vs. Jonathan) had died within 24 hours, 30 days, or 6 months of the initial EMS encounter. The abstractor was blinded to the study hypothesis.
RESULTS: 205 subjects were identified; the median (IQR) age was 41 (29-53) years. 27 (13%) were female. One subject (0.49%) died within 24 hours of the initial EMS encounter. The cause of death (COD) was coronary artery disease and heroin use. Two additional subjects (1. %) died within 30 days. One of these subjects died 6 days later; the COD is unknown. The other subject died 20 days after the EMS encounter; the COD was cardiovascular disease and liver cirrhosis. No additional subjects were identified at the 6 month follow up. A third subject died of a heroin overdose 16 months after the initial EMS encounter, but was beyond the pre-defined follow up period.
CONCLUSIONS: The practice of receiving pre-hospital naloxone by paramedics and subsequently refusing care is associated with an extremely low short- and intermediate-term mortality. Despite an evolving pattern of opioid abuse, the results of this study are consistent with previously reported studies.

Entities:  

Keywords:  AMA; EMS; against medical advice; death; naloxone; opiate

Mesh:

Substances:

Year:  2016        PMID: 27018626     DOI: 10.3109/10903127.2016.1142626

Source DB:  PubMed          Journal:  Prehosp Emerg Care        ISSN: 1090-3127            Impact factor:   3.077


  9 in total

Review 1.  Naloxone dosage for opioid reversal: current evidence and clinical implications.

Authors:  Rachael Rzasa Lynn; J L Galinkin
Journal:  Ther Adv Drug Saf       Date:  2017-12-13

2.  Ambulance Calls for Substance-Related Issues Before and After COVID-19.

Authors:  Scott G Weiner; Rebecca E Cash; Michelle Hendricks; Sanae El Ibrahimi; Olesya Baker; Raghu R Seethala; Gregory Peters; Scott A Goldberg
Journal:  Prehosp Emerg Care       Date:  2020-12-15       Impact factor: 3.077

3.  Patterns of polysubstance use and overdose among people who inject drugs in Baltimore, Maryland: A latent class analysis.

Authors:  Kristin E Schneider; Ju Nyeong Park; Sean T Allen; Brian W Weir; Susan G Sherman
Journal:  Drug Alcohol Depend       Date:  2019-06-06       Impact factor: 4.492

4.  Multiple Naloxone Administrations Among Emergency Medical Service Providers is Increasing.

Authors:  Mark Faul; Peter Lurie; Jeremiah M Kinsman; Michael W Dailey; Charmaine Crabaugh; Scott M Sasser
Journal:  Prehosp Emerg Care       Date:  2017-05-08       Impact factor: 3.077

5.  Legal Authority for Emergency Medical Services to Increase Access to Buprenorphine Treatment for Opioid Use Disorder.

Authors:  Corey S Davis; Derek H Carr; Melody J Glenn; Elizabeth A Samuels
Journal:  Ann Emerg Med       Date:  2021-03-27       Impact factor: 6.762

Review 6.  Intranasal naloxone and related strategies for opioid overdose intervention by nonmedical personnel: a review.

Authors:  Christa R Lewis; Hoa T Vo; Marc Fishman
Journal:  Subst Abuse Rehabil       Date:  2017-10-11

7.  Administration of Naloxone by Prehospital Personnel: A Retrospective Analysis.

Authors:  Kaitlin M Bowers; Judd Shelton; Eric Cortez; Robert Lowe; John Casey; Andrew Little
Journal:  Cureus       Date:  2019-09-09

8.  Perspectives from law enforcement officers who respond to overdose calls for service and administer naloxone.

Authors:  Hope M Smiley-McDonald; Peyton R Attaway; Nicholas J Richardson; Peter J Davidson; Alex H Kral
Journal:  Health Justice       Date:  2022-02-25

9.  Opportunities for Emergency Medical Services Intervention to Prevent Opioid Overdose Mortality.

Authors:  Elizabeth H Barefoot; Julianne M Cyr; Jane H Brice; Michael W Bachman; Jefferson G Williams; Jose G Cabanas; Kyle M Herbert
Journal:  Prehosp Emerg Care       Date:  2020-04-02       Impact factor: 3.077

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.