| Literature DB >> 27017870 |
Neal Bhutiani1, Robert C G Martin2.
Abstract
Until recently, hepatic arterial therapies (HAT) had been used for colorectal liver metastases after failure of first-, second-, and third-line chemotherapies. HAT has gained greater acceptance in patients with liver-dominant colorectal metastases after failure of surgery or systemic chemotherapy. The current data demonstrate that HAT is a safe and effective option for preoperative downsizing, optimizing the time to surgery, limiting non-tumor-bearing liver toxicity, and improving overall survival after surgery in patients with colorectal liver-only metastases. The aim of this review is to present the current data for HAT in liver-only and liver-dominant colorectal liver metastases.Entities:
Keywords: Chemoembolization; Colorectal liver metastases; Drug-eluting beads (DEB); Hepatic arterial therapy (HAT); Hepatic artery infusion (HAI); Surgical resection; Yttrium-90
Mesh:
Substances:
Year: 2016 PMID: 27017870 DOI: 10.1016/j.suc.2015.12.003
Source DB: PubMed Journal: Surg Clin North Am ISSN: 0039-6109 Impact factor: 2.741