| Literature DB >> 27017109 |
Julia Mortera1, Carla Vecchiotti2, Silvia Zoppis2, Sara Merigioli3.
Abstract
Here we analyse a complex disputed paternity case, where the DNA of the putative father was extracted from his corpse that had been inhumed for over 20 years. This DNA was contaminated and appears to be a mixture of at least two individuals. Furthermore, the mother's DNA was not available. The DNA mixture was analysed so as to predict the most probable genotypes of each contributor. The major contributor's profile was then used to compute the likelihood ratio for paternity. We also show how to take into account a dropout allele and the possibility of mutation in paternity testing.Keywords: DNA mixtures; Deconvolution; Disputed paternity; Dropout allele; Likelihood ratio; Mutation
Mesh:
Substances:
Year: 2016 PMID: 27017109 DOI: 10.1016/j.fsigen.2016.02.014
Source DB: PubMed Journal: Forensic Sci Int Genet ISSN: 1872-4973 Impact factor: 4.882