| Literature DB >> 27016779 |
Nora Martínez1, Cyntia E Abán2, Gustavo F Leguizamón3, Alicia E Damiano4, Mariana G Farina2.
Abstract
Preeclampsia is a multisystem disorder unique to human pregnancy, characterized by abnormal placentation. Although its causes remain unclear, it is known that the expression of several transporters is altered. Transient receptor potential vanilloid 1 (TRPV-1) is a nonselective cation channel, present in human placenta. Here, we evaluated the expression of TRPV-1 in preeclamptic placentas. We observed a deregulation in TRPV-1 expression in these placentas which may explain the impaired Ca(2+) homeostasis found in preeclampsia.Entities:
Keywords: Preeclampsia; TRPV-1; Trophoblast
Mesh：
Substances：
Year: 2016 PMID： 27016779 DOI： 10.1016/j.placenta.2016.02.008
Source DB: PubMed Journal: Placenta ISSN： 0143-4004 Impact factor: 3.481