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Literature DB >> 27016220

Interactions of porcine circovirus 2 with its hosts.

Linzhu Ren¹, Xinrong Chen², Hongsheng Ouyang².

Abstract

Porcine circovirus 2 (PCV2) can cause porcine circovirus diseases and porcine circovirus-associated diseases (PCVD/PCVAD), which are widely presented in swine-producing countries. Since the discovery of this virus, considerable efforts have been devoted to understanding this pathogen and its interactions with its host. Here, we review the current state of knowledge on interactions between host cell factors and PCV2 with respect to viral proliferation, virus-induced cell apoptosis and autophagy, and host antiviral defenses during PCV2 infection. We also review mouse model systems for PCV2 infection.

Entities: Disease Species

Keywords: Cell; Infection; Interaction; Open reading frame (ORF); Porcine circovirus 2 (PCV2); Signaling pathway

Mesh：

Year: 2016 PMID： 27016220 DOI： 10.1007/s11262-016-1326-x

Source DB: PubMed Journal: Virus Genes ISSN： 0920-8569 Impact factor: 2.332

122 in total

10. A field efficacy and safety trial in the Netherlands in pigs vaccinated at 3 weeks of age with a ready-to-use porcine circovirus type 2 and Mycoplasma hyopneumoniae combined vaccine.

Authors: Luuk Kaalberg; Victor Geurts; Rika Jolie
Journal: Porcine Health Manag Date: 2017-11-09

Interactions of porcine circovirus 2 with its hosts.

1. Binding and entry characteristics of porcine circovirus 2 in cells of the porcine monocytic line 3D4/31.

2. CD44 deficiency leads to decreased proinflammatory cytokine production in lung induced by PCV2 in mice.

3. Hsp70 positively regulates porcine circovirus type 2 replication in vitro.

4. Regulator of G protein signalling 16 is a target for a porcine circovirus type 2 protein.

5. Identification and characterization of two novel transcription units of porcine circovirus 2.

6. Enhanced replication of porcine circovirus type 2 (PCV2) in a homogeneous subpopulation of PK15 cell line.

7. Porcine circovirus-2 capsid protein induces cell death in PK15 cells.

8. Phylogenetic characterization of porcine circovirus type 2 in PMWS and PDNS Korean pigs between 1999 and 2006.

9. Cellular promyelocytic leukemia protein is an important dengue virus restriction factor.

10. Proteomic alteration of PK-15 cells after infection by porcine circovirus type 2.

1. Porcine Circovirus Type 2 Suppresses IL-12p40 Induction via Capsid/gC1qR-Mediated MicroRNAs and Signalings.

2. Mink Circovirus Can Infect Minks, Foxes and Raccoon Dogs.

3. Phylogenetic analysis of porcine circovirus type 2 (PCV2) between 2015 and 2018 in Henan Province, China.

4. Porcine circovirus genotypes and their copathogens in pigs with respiratory disease in southern provinces of Vietnam.

5. Immunogenicity evaluation of inactivated virus and purified proteins of porcine circovirus type 2 in mice.

Review 6. Co-Infection of Swine with Porcine Circovirus Type 2 and Other Swine Viruses.

7. Human cells are permissive for the productive infection of porcine circovirus type 2 in vitro.

8. Porcine HMGCR Inhibits Porcine Circovirus Type 2 Infection by Directly Interacting with the Viral Proteins.

9. Immunogenicity of plant-produced porcine circovirus-like particles in mice.

10. A field efficacy and safety trial in the Netherlands in pigs vaccinated at 3 weeks of age with a ready-to-use porcine circovirus type 2 and Mycoplasma hyopneumoniae combined vaccine.